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[Cytomegalovirus infection in neonates. Diagnosis and therapeutic experiences].

  • Academic Journal
  • Fjaer RB; Forsvarets sanitet, Oslo mil/Huseby.
    Abrahamsen TG
    Bruu AL
    Hansen TW
  • Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke [Tidsskr Nor Laegeforen] 1997 Apr 20; Vol. 117 (10), pp. 1460-4.
  • Norwegian
  • Approximately 0.5-1% of all newborns are born infected with cytomegalovirus (CMV), but of these only one out of ten show symptoms at birth, most often with hepatosplenomegaly, thrombocytopenia, and/or brain affection. Of the remaining nine, one may later develop sequelae with hearing loss and/or mental retardation. CMV infection may also be acquired perinatally or in the newborn period, and may cause pneumonia and/or sepsis, possibly also gastrointestinal symptoms like blood in the stool, and poor weight-gain. We have diagnosed CMV infection in ten neonates and infants, and describe these patients in terms of symptoms, diagnosis and treatment. Ganciclovir is being tested in clinical trials as a treatment for congenital CMV infection, and was given to two of our patients with apparently good results.
Additional Information
Cytomegalovirusinfeksjon hos nyfødte. Erfaringer med diagnostikk og behandling.
Publisher: Norske Laegeforening Country of Publication: Norway NLM ID: 0413423 Publication Model: Print Cited Medium: Print ISSN: 0029-2001 (Print) Linking ISSN: 00292001 NLM ISO Abbreviation: Tidsskr Nor Laegeforen Subsets: MEDLINE
Publication: Oslo : Norske Laegeforening
Original Publication: Chistiania : Alb. Cammermeyer, 1880-
0 (Antiviral Agents)
P9G3CKZ4P5 (Ganciclovir)
Date Created: 19970420 Date Completed: 19970620 Latest Revision: 20131121