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The impact of the COVID-19 pandemic on ICU clinical trials: a description of one research team's experience.
Publication Type: Academic Journal
Source(s): Trials; 5/11/2023, Vol. 24 Issue 1, p1-12, 12p, 4 Charts, 1 Graph
Abstract: Copyright of Trials is the property of BioMed Central and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email article...
Inhaled aviptadil for the possible treatment of COVID-19 in patients at high risk for ARDS: study protocol for a randomized, placebo-controlled, and multicenter trial.
Publication Type: Academic Journal
Source(s): Trials; 9/20/2022, Vol. 23 Issue 1, p1-13, 13p, 1 Black and White Photograph, 1 Chart
Abstract: Copyright of Trials is the property of BioMed Central and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email article...
Quantifying the impact of the COVID-19 pandemic on clinical trial screening rates over time in 37 countries.
Publication Type: Academic Journal
Source(s): Trials. 4/4/2023, Vol. 24 Issue 1, p1-10. 10p. 1 Chart, 5 Graphs.
Abstract: The COVID-19 pandemic has had an unprecedented and disruptive impact on people's health and lives worldwide. In addition to burdening people's health in the short-term in the form of infection, illness, and mortality, there has been an enormous negativ...
Impact of the COVID-19 pandemic on a clinical trial of pneumococcal vaccine scheduling (PVS) in rural Gambia.
Publication Type: Academic Journal
Source(s): Trials. 4/13/2023, Vol. 24 Issue 1, p1-9. 9p. 2 Charts, 1 Graph.
Abstract: The COVID-19 pandemic represents an unprecedented challenge for clinical research. The Pneumococcal Vaccine Schedules (PVS) study is a non-inferiority, interventional trial in which infants resident in 68 geographic clusters are randomised to two diffe...
Evidence of secular trends during the COVID-19 pandemic in a stepped wedge cluster randomized trial examining sexual and reproductive health outcomes among Indigenous youth.
Publication Type: Academic Journal
Source(s): Trials. 4/1/2023, Vol. 24 Issue 1, p1-12. 12p. 5 Charts.
Abstract: Background: Nen ŨnkUmbi/EdaHiYedo ("We Are Here Now," or NE) is an intervention to prevent STIs, HIV, HCV, and teen pregnancy among Assiniboine and Sioux youth of the Fort Peck Reservation in the state of Montana in the USA. A cluster-randomized steppe...
Participant recruitment, baseline characteristics and at-home-measurements of cardiometabolic risk markers: insights from the Supreme Nudge parallel cluster-randomised controlled supermarket trial.
Publication Type: Academic Journal
Source(s): Trials. 3/2/2023, Vol. 24 Issue 1, p1-15. 15p. 1 Diagram, 5 Charts.
Abstract: Background: Recruiting participants for lifestyle programmes is known to be challenging. Insights into recruitment strategies, enrolment rates and costs are valuable but rarely reported. We provide insight into the costs and results of used recruitment...
The COMFORT trial: a randomised control trial comparing group-based COMpassion-FOcussed therapy and breathing pattern ReTraining with treatment as usual on the psychological functioning of patients diagnosed with cancer recurrence during COVID.
Publication Type: Academic Journal
Source(s): Trials. 2/6/2023, Vol. 24 Issue 1, p1-13. 13p. 1 Diagram, 2 Charts.
Abstract: Background: A cancer diagnosis is a known precipitant of psychological distress, with fear of recurrence being a well-documented distressing consequence of cancer. Cancer recurrence often results in an additional psychological burden, which may exacerb...
The future is now: our experience starting a remote clinical trial during the beginning of the COVID-19 pandemic.
Publication Type: Report
Source(s): Trials [Trials] 2021 Sep 07; Vol. 22 (1), pp. 603. Date of Electronic Publication: 2021 Sep 07.
Abstract: Background: The World Health Organization declared the outbreak of SARS-CoV-2 a pandemic on February 11, 2020. This organism causes COVID-19 disease and the rapid rise in cases and geographic spread strained healthcare systems. Clinical research trials...
Evidence of secular trends during the COVID-19 pandemic in a stepped wedge cluster randomized trial examining sexual and reproductive health outcomes among Indigenous youth
Publication Type: Academic Journal
Source(s): Trials, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract: Abstract Background Nen ŨnkUmbi/EdaHiYedo (“We Are Here Now,” or NE) is an intervention to prevent STIs, HIV, HCV, and teen pregnancy among Assiniboine and Sioux youth of the Fort Peck Reservation in the state of Montana in the USA. A cluster-randomize...
Research interrupted: applying the CONSERVE 2021 Statement to a randomized trial of rehabilitation during critical illness affected by the COVID-19 pandemic.
Publication Type: Academic Journal
Source(s): Trials. 9/2/2022, Vol. 23 Issue 1, p1-12. 12p. 3 Diagrams, 4 Charts, 2 Graphs.
Abstract: Rationale: The COVID-19 pandemic disrupted non-COVID critical care trials globally as intensive care units (ICUs) prioritized patient care and COVID-specific research. The international randomized controlled trial CYCLE (Critical Care Cycling to Improv...