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Exploring COVID-19 transmission patterns and key factors during epidemics caused by three major strains in Asia.
Publication Type: Academic Journal
Source(s): Journal of Theoretical Biology. Jan2023, Vol. 557, pN.PAG-N.PAG. 1p.
Abstract: • Periods of epidemics induced by different strains in Asian countries were classified by k-shape and hierarchical clustering methods. • Using correlation and regression analysis to explore the results of clustering Asian countries. • Revealing the rea...
Emergence of SARS-CoV-2 Omicron (B.1.1.529) variant, salient features, high global health concerns and strategies to counter it amid ongoing COVID-19 pandemic.
Publication Type: Academic Journal
Source(s): Environmental Research. Jun2022, Vol. 209, pN.PAG-N.PAG. 1p.
Abstract: Since the appearance in the late of December 2019, SARS-CoV-2 is rapidly evolving and mutating continuously, giving rise to various variants with variable degrees of infectivity and lethality. The virus that initially appeared in China later mutated se...
Identification of potential COVID-19 treatment compounds which inhibit SARS Cov2 prototypic, Delta and Omicron variant infection.
Publication Type: Academic Journal
Source(s): Virology. Jul2022, Vol. 572, p64-71. 8p.
Abstract: Recurrent waves of COVID19 remain a major global health concern. Repurposing either FDA-approved or clinically advanced drug candidates can save time and effort required for validating the safety profile and FDA approval. However, the selection of appr...
SARS-CoV-2 and influenza co-infection: A cross-sectional study in central Missouri during the 2021–2022 influenza season.
Publication Type: Academic Journal
Source(s): Virology. Nov2022, Vol. 576, p105-110. 6p.
Abstract: As SARS-CoV-2 and influenza viruses co-circulate, co-infections with these viruses generate an increasing concern to public health. To evaluate the prevalence and clinical impacts of SARS-CoV-2 and influenza A virus co-infections during the 2021–2022 i...
Diagnostic performance of a novel antigen-capture ELISA for the detection of SARS-CoV-2.
Publication Type: Academic Journal
Source(s): Analytical Biochemistry. Apr2023, Vol. 666, pN.PAG-N.PAG. 1p.
Abstract: The coronavirus disease 2019 (COVID-19) pandemic is a serious health problem worldwide. Early virus detection is essential for disease control and management. Viral antigen detection by ELISA is a cost-effective, rapid, and accurate antigen diagnostic ...
Stability of SARS-CoV-2 variants of concern (Delta and Omicron) on surfaces at room temperature.
Publication Type: Academic Journal
Source(s): Virology. Jun2023, Vol. 583, p27-28. 2p.
Abstract: Surfaces contaminated with infectious SARS-CoV-2 particles have the potential to cause human infection and any increase in surface survivability of a SARS-CoV-2 variant may increase its prevalence over other variants. This study investigated whether th...
The original strain of SARS-CoV-2, the Delta variant, and the Omicron variant infect microglia efficiently, in contrast to their inability to infect neurons: Analysis using 2D and 3D cultures.
Publication Type: Academic Journal
Source(s): Experimental Neurology. May2023, Vol. 363, pN.PAG-N.PAG. 1p.
Abstract: COVID-19 causes neurological damage, systemic inflammation, and immune cell abnormalities. COVID-19-induced neurological impairment may be caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which directly infects cells of the centr...
Ascertainment rate of SARS-CoV-2 infections from healthcare and community testing in the UK.
Publication Type: Academic Journal
Source(s): Journal of Theoretical Biology. Feb2023, Vol. 558, pN.PAG-N.PAG. 1p.
Abstract: The proportion of SARS-CoV-2 infections ascertained through healthcare and community testing is generally unknown and expected to vary depending on natural factors and changes in test-seeking behaviour. Here we use population surveillance data and repo...
Human 14-3-3 Proteins Site-selectively Bind the Mutational Hotspot Region of SARS-CoV-2 Nucleoprotein Modulating its Phosphoregulation.
Publication Type: Academic Journal
Source(s): Journal of Molecular Biology. Jan2023, Vol. 435 Issue 2, pN.PAG-N.PAG. 1p.
Abstract: [Display omitted] • S197 and T205 are mutually exclusive 14-3-3-binding phosphosites in SARS-CoV-2 N. • T205 is the preferred binding site by all seven human 14-3-3 isoforms. • The seven 14-3-3 proteins show the unique T205/S197 phosphopeptide binding ...
On the peptide binding affinity changes in population-specific HLA repertoires to the SARS-CoV-2 variants Delta and Omicron.
Publication Type: Academic Journal
Source(s): Journal of Autoimmunity. Dec2022, Vol. 133, pN.PAG-N.PAG. 1p.
Abstract: To investigate the changes of Spike protein-HLA binding affinity profiles between the Wuhan strain and two dominant variants, the Delta and the Omicron strains, among the Taiwanese, the British and the Russian populations. The HLA frequencies and the H...