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Timing of REGEN-COV administration and progression to severe COVID-19.
Publication Type: Academic Journal
Source(s): Journal of Infection & Chemotherapy (Elsevier Inc.). Nov2022, Vol. 28 Issue 11, p1459-1463. 5p.
Abstract: Several clinical trials have demonstrated that REGEN-COV (casirivimab and imdevimab) decreases the risk of hospitalization and death among COVID-19 patients. However, these trials did not evaluate the optimal timing of its administration, and evidence ...
Three waves changes, new variant strains, and vaccination effect against COVID-19 pandemic.
Publication Type: Academic Journal
Source(s): International Journal of Biological Macromolecules. Apr2022, Vol. 204, p161-168. 8p.
Abstract: It has been more than one year since the first case of the coronaviruses was infected by COVID-19 in China. The world witnessed three waves of the corona virus till now, and more upcoming is expected, whereas several challenges are presented. Empirical...
A Preliminary Genomic Analysis of the Omicron Variants of SARS-CoV-2 in Central India During the third wave of the COVID-19 Pandemic.
Publication Type: Academic Journal
Source(s): Archives of Medical Research. Sep2022, Vol. 53 Issue 6, p574-584. 11p.
Abstract: Omicron was detected in South Africa for the first time at the month of November 2021, from then it expanded swiftly over the world, outcompeting other SARS-CoV-2 variants such as Delta. The toxicity, resistance to antiviral medicines, transmissibility...
Genomic and epidemiologic surveillance of SARS-CoV-2 in Southern Brazil and identification of a new Omicron-L452R sublineage.
Publication Type: Academic Journal
Source(s): Virus Research. Nov2022, Vol. 321, pN.PAG-N.PAG. 1p.
Abstract: • Omicron genetic and epidemiological characteristics in Southern, Brazil. • Completely Omicron mutational data. • Gamma variant was completely displaced by Omicron in a short period of time. • First time identification of a new Omicron variant of conc...
Omicron variant: Current insights and future directions.
Publication Type: Academic Journal
Source(s): Microbiological Research. Dec2022, Vol. 265, pN.PAG-N.PAG. 1p.
Abstract: The global COVID-19 outbreak has returned with the identification of the SARS-CoV-2 Omicron variant (B.1.1.529) after appearing to be persistently spreading for the more than past two years. In comparison to prior SARS-CoV-2 variants, this new variant ...
Development of a simple genotyping method based on indel mutations to rapidly screen SARS-CoV-2 circulating variants: Delta, Omicron BA.1 and BA.2.
Publication Type: Academic Journal
Source(s): Journal of Virological Methods. Sep2022, Vol. 307, pN.PAG-N.PAG. 1p.
Abstract: The high need of rapid and flexible tools that facilitate the identification of circulating SARS-CoV-2 Variants of Concern (VOCs) remains crucial for public health system monitoring. Here, we develop allele-specific (AS)-qPCR assays targeting three rec...
SARS-CoV-2 multiplex RT-PCR to detect variants of concern (VOCs) in Malaysia, between January to May 2021.
Publication Type: Academic Journal
Source(s): Journal of Virological Methods. Mar2022, Vol. 301, pN.PAG-N.PAG. 1p.
Abstract: • Two multiplex real-time PCR assays for SARS-CoV-2 spike variants were tested. • The assays detect spike HV69/70 deletion, Y144 deletion, E484K, N501Y, and P681H. • The assays have 98.7–100 % sensitivity compared to next-generation sequencing (NGS). •...
Mutational dynamics across VOCs in International travellers and Community transmission underscores importance of Spike-ACE2 interaction.
Publication Type: Academic Journal
Source(s): Microbiological Research. Sep2022, Vol. 262, pN.PAG-N.PAG. 1p.
Abstract: Emergence of SARS-CoV-2 VOCs at different time points through COVID-19 pandemic raised concern for increased transmissibility, infectivity and vaccination breakthroughs. 1567 international travellers plus community transmission COVID-19 cases were anal...
A nanoparticle-based COVID-19 vaccine candidate elicits broad neutralizing antibodies and protects against SARS-CoV-2 infection.
Publication Type: Academic Journal
Source(s): Nanomedicine: Nanotechnology, Biology & Medicine; Aug2022, Vol. 44, pN.PAG-N.PAG, 1p
Abstract: Copyright of Nanomedicine: Nanotechnology, Biology & Medicine is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, us...
Low Covid-19 Related Mortality Among Lung Transplant Recipients at a Single Center.
Publication Type: Academic Journal
Source(s): Journal of Heart & Lung Transplantation. Apr2023:Supplement, Vol. 42 Issue 4, pS308-S309. 2p.
Abstract: The omicron variant era led to a dramatic increase in COVID-19 infection in lung transplant recipients (LTR). We previously described our experience with COVID-19 in LTR during the wild type and delta variant eras. Here we provide an update on short an...