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Retrospective Analysis of the Effectiveness of Remdesivir in COVID-19 Treatment during Periods Dominated by Delta and Omicron SARS-CoV-2 Variants in Clinical Settings.
Publication Type: Academic Journal
Source(s): Journal of Clinical Medicine. Mar2023, Vol. 12 Issue 6, p2371. 16p.
Abstract: Continuous evaluation of real-world treatment effectiveness of COVID-19 medicines is required due to the ongoing evolution of SARS-CoV-2 and the possible emergence of resistance. Therefore, this study aimed to analyze, in a retrospective manner, the ou...
Research from Jan Kochanowski University Yields New Findings on Remdesivir (Retrospective Analysis of the Effectiveness of Remdesivir in COVID-19 Treatment during Periods Dominated by Delta and Omicron SARS-CoV-2 Variants in Clinical Settings).
Publication Type: Periodical
Source(s): NewsRx COVID-19 Weekly; 4/9/2023, p51-51, 1p
Abstract: Copyright of NewsRx COVID-19 Weekly is the property of NewsRx and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email...
Evolving Real-World Effectiveness of Monoclonal Antibodies for Treatment of COVID-19: A Cohort Study.
Publication Type: Academic Journal
Source(s): Annals of Internal Medicine; Apr2023, Vol. 176 Issue 4, p496-504, 9p, 1 Diagram, 3 Charts, 2 Graphs
Abstract: Copyright of Annals of Internal Medicine is the property of American College of Physicians and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users ...
Dok3 restrains neutrophil production of calprotectin during TLR4 sensing of SARS-CoV-2 spike protein.
Publication Type: Academic Journal
Source(s): Frontiers in Immunology; 9/12/2022, Vol. 12, p1-14, 14p
Abstract: Copyright of Frontiers in Immunology is the property of Frontiers Media S.A. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, dow...
Understanding the Driving Forces That Trigger Mutations in SARS-CoV-2: Mutational Energetics and the Role of Arginine Blockers in COVID-19 Therapy.
Publication Type: Academic Journal
Source(s): Viruses (1999-4915). May2022, Vol. 14 Issue 5, p1029-1029. 31p.
Abstract: SARS-CoV-2 is a global challenge due to its ability to mutate into variants that spread more rapidly than the wild-type virus. Because the molecular biology of this virus has been studied in such great detail, it represents an archetypal paradigm for r...
Identification of potential COVID-19 treatment compounds which inhibit SARS Cov2 prototypic, Delta and Omicron variant infection.
Publication Type: Academic Journal
Source(s): Virology. Jul2022, Vol. 572, p64-71. 8p.
Abstract: Recurrent waves of COVID19 remain a major global health concern. Repurposing either FDA-approved or clinically advanced drug candidates can save time and effort required for validating the safety profile and FDA approval. However, the selection of appr...
Peptidomimetic inhibitors of TMPRSS2 block SARS-CoV-2 infection in cell culture.
Publication Type: Academic Journal
Source(s): Communications Biology; 7/8/2022, Vol. 5 Issue 1, p1-12, 12p
Abstract: Copyright of Communications Biology is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download,...
First-in-class trispecific VHH-Fc based antibody with potent prophylactic and therapeutic efficacy against SARS-CoV-2 and variants.
Publication Type: Academic Journal
Source(s): Scientific Reports; 3/9/2022, Vol. 12 Issue 1, p1-11, 11p
Abstract: Copyright of Scientific Reports is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or ...
Single-Domain Antibodies Efficiently Neutralize SARS-CoV-2 Variants of Concern.
Publication Type: Academic Journal
Source(s): Frontiers in Immunology; 2/24/2022, Vol. 13, p1-9, 9p
Abstract: Copyright of Frontiers in Immunology is the property of Frontiers Media S.A. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, dow...
Real-World Effectiveness of Sotrovimab for the Early Treatment of COVID-19 During SARS-CoV-2 Delta and Omicron Waves in the USA.
Publication Type: Academic Journal
Source(s): Infectious Diseases & Therapy; Feb2023, Vol. 12 Issue 2, p607-621, 15p
Abstract: Copyright of Infectious Diseases & Therapy is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, do...