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Comparative Analysis of a Human Neutralizing mAb Specific for SARS-CoV-2 Spike-RBD with Cilgavimab and Tixagevimab for the Efficacy on the Omicron Variant in Neutralizing and Detection Assays.
Publication Type: Academic Journal
Source(s): International Journal of Molecular Sciences. Jun2023, Vol. 24 Issue 12, p10053. 17p.
Abstract: The recent pandemic years have prompted the scientific community to increasingly search for and adopt new and more efficient therapeutic and diagnostic approaches to deal with a new infection. In addition to the development of vaccines, which has playe...
Quantitative profiling of N-glycosylation of SARS-CoV-2 spike protein variants.
Publication Type: Academic Journal
Source(s): Glycobiology; Mar2023, Vol. 33 Issue 3, p188-202, 15p
Abstract: Copyright of Glycobiology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, downl...
A high scale SARS-CoV-2 profiling by its whole-genome sequencing using Oxford Nanopore Technology in Kazakhstan.
Publication Type: Academic Journal
Source(s): Frontiers in Genetics; 9/2/2022, Vol. 13, p1-8, 8p
Abstract: Copyright of Frontiers in Genetics is the property of Frontiers Media S.A. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, downl...
In Silico Genome Analysis Reveals the Evolution and Potential Impact of SARS-CoV-2 Omicron Structural Changes on Host Immune Evasion and Antiviral Therapeutics.
Publication Type: Academic Journal
Source(s): Viruses (1999-4915). Nov2022, Vol. 14 Issue 11, p2461. 14p.
Abstract: New variants of SARS-CoV-2 continue to evolve. The novel SARS-CoV-2 variant of concern (VOC) B.1.1.529 (Omicron) was particularly menacing due to the presence of numerous consequential mutations. In this study, we reviewed about 12 million SARS-CoV-2 g...
Inhibition of the Cell Uptake of Delta and Omicron SARS-CoV-2 Pseudoviruses by N -Acetylcysteine Irrespective of the Oxidoreductive Environment.
Publication Type: Academic Journal
Source(s): Cells (2073-4409). Oct2022, Vol. 11 Issue 20, p3313-N.PAG. 13p.
Abstract: The binding of SARS-CoV-2 spikes to the cell receptor angiotensin-converting enzyme 2 (ACE2) is a crucial target both in the prevention and in the therapy of COVID-19. We explored the involvement of oxidoreductive mechanisms by investigating the effect...
Effect of Moderate to Severe Hepatic Steatosis on Vaccine Immunogenicity against Wild-Type and Mutant Virus and COVID-19 Infection among BNT162b2 Recipients.
Publication Type: Academic Journal
Source(s): Vaccines. Mar2023, Vol. 11 Issue 3, p497. 11p.
Abstract: Background: We aimed to investigate the effect of non-alcoholic fatty liver disease (NAFLD) on BNT162b2 immunogenicity against wild-type SARS-CoV-2 and variants and infection outcome, as data are lacking. Methods: Recipients of two doses of BNT162b2 we...
Mathematical modeling of respiratory viral infection and applications to SARS‐CoV‐2 progression.
Publication Type: Academic Journal
Source(s): Mathematical Methods in the Applied Sciences. 1/30/2023, Vol. 46 Issue 2, p1740-1751. 12p.
Abstract: Viral infection in cell culture and tissue is modeled with delay reaction‐diffusion equations. It is shown that progression of viral infection can be characterized by the viral replication number, time‐dependent viral load, and the speed of infection s...
Nanostructures for prevention, diagnosis, and treatment of viral respiratory infections: from influenza virus to SARS-CoV-2 variants.
Publication Type: Academic Journal
Source(s): Journal of nanobiotechnology [J Nanobiotechnology] 2023 Jun 21; Vol. 21 (1), pp. 199. Date of Electronic Publication: 2023 Jun 21.
Abstract: Viruses are a major cause of mortality and socio-economic downfall despite the plethora of biopharmaceuticals designed for their eradication. Conventional antiviral therapies are often ineffective. Live-attenuated vaccines can pose a safety risk due to...
Genomic surveillance of SARS‐CoV‐2 strains circulating in Iran during six waves of the pandemic.
Publication Type: Academic Journal
Source(s): Influenza & Other Respiratory Viruses. Apr2023, Vol. 17 Issue 4, p1-8. 8p.
Abstract: Background: SARS‐CoV‐2 genomic surveillance is necessary for the detection, monitoring, and evaluation of virus variants, which can have increased transmissibility, disease severity, or other adverse effects. We sequenced 330 SARS‐CoV‐2 genomes during ...
Hong Kong Surge; South Korea Cases Rise to Record: Virus Update.
Publication Type: Periodical
Source(s): Bloomberg.com; 2/13/2022, pN.PAG-N.PAG, 1p
Abstract: Copyright of Bloomberg.com is the property of Bloomberg, L.P. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email...