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    • KDM5 Lysine Demethylases in Pathogenesis, from Basic Science Discovery to the Clinic.

    Publication Type: Academic Journal

    Source(s): Advances in experimental medicine and biology [Adv Exp Med Biol] 2023; Vol. 1433, pp. 113-137.

    Authors:

    Abstract: The histone lysine demethylase 5 (KDM5) family proteins are Fe 2+ and α-ketoglutarate-dependent dioxygenases, with jumonji C (JmjC) domain as their catalytic core and several plant homeodomains (PHDs) to bind different histone methylation marks. These ...

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