Abstract:The histone lysine demethylase 5 (KDM5) family proteins are Fe 2+ and α-ketoglutarate-dependent dioxygenases, with jumonji C (JmjC) domain as their catalytic core and several plant homeodomains (PHDs) to bind different histone methylation marks. These ...
Source(s):Journal of neural transmission (Vienna, Austria : 1996) [J Neural Transm (Vienna)] 2021 Jun; Vol. 128 (6), pp. 717-734. Date of Electronic Publication: 2021 Jun 11.
Abstract:Background: Based on recent evidence, more than 200 susceptibility genes have been identified to be associated with autism until now. Correspondingly, cytogenetic abnormalities have been reported for almost every chromosome. While the results of multip...