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Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer.

Publication Type: Academic Journal

Source(s): Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 May 01; Vol. 115 (18), pp. 4767-4772. Date of Electronic Publication: 2018 Apr 18.

Authors:

Abstract: To evaluate whether germline variants in genes encoding pancreatic secretory enzymes contribute to pancreatic cancer susceptibility, we sequenced the coding regions of CPB1 and other genes encoding pancreatic secretory enzymes and known pancreatitis su...

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