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Feeling the forces within materials: bringing inter-molecular bonding to the fore using embodied modelling.

Publication Type: Academic Journal

Source(s): International Journal of Science Education. Sep2018, Vol. 40 Issue 13, p1567-1586. 20p.

Abstract: We developed a computerised simulation that utilises embodied modelling by letting students play the role of particles in a liquid. We compared the learning of two eight-grade classrooms that used the embodied modelling simulation during a weeklong lea...

Inter-assay variability in automated serum free light chain assays and their use in the clinical laboratory.

Publication Type: Academic Journal

Source(s): Critical Reviews in Clinical Laboratory Sciences. Mar2020, Vol. 57 Issue 2, p73-85. 13p. 4 Charts.

Abstract: Serum κ and λ free light chain levels are markers of plasma cell proliferation, and their measurements have been included in recent guidelines by the International Myeloma Working Group for the management of patients with plasma cellular dyscrasias. Fi...

Mean platelet volume in familial Mediterranean fever related AA amyloidosis and comparison with common primary glomerular diseases

Publication Type: Academic Journal

Source(s): Turkish journal of medical sciences [Turk J Med Sci] 2021 Oct 21; Vol. 51 (5), pp. 2364-2368. Date of Electronic Publication: 2021 Oct 21.

Abstract: Background/aim: Compared to healthy controls, mean platelet volume (MPV) is frequently higher in patients with Familial Mediterranean fever (FMF) but lower in AA amyloidosis patients. The reason for the difference in MPV levels in FMF patients with and...

Inter-level Scaffolding and Sequences of Representational Activities in Teaching a Chemical System with Graphical Simulations.

Publication Type: Academic Journal

Source(s): Journal of Science Education & Technology; Oct2016, Vol. 25 Issue 5, p715-730, 16p, 1 Color Photograph, 3 Diagrams, 3 Charts, 2 Graphs


Abstract: Copyright of Journal of Science Education & Technology is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users m...

Use of biomarkers to diagnose and manage cardiac amyloidosis.

Publication Type: Academic Journal

Source(s): European journal of heart failure [Eur J Heart Fail] 2021 Feb; Vol. 23 (2), pp. 217-230. Date of Electronic Publication: 2021 Feb 21.

Abstract: Amyloidoses are characterized by the tissue accumulation of misfolded proteins into insoluble fibrils. The two most common types of systemic amyloidosis result from the deposition of immunoglobulin light chains (AL) and wild-type or variant transthyret...

Association of anxiety with subcortical amyloidosis in cognitively normal older adults.

Publication Type: Academic Journal

Source(s): Molecular psychiatry [Mol Psychiatry] 2020 Oct; Vol. 25 (10), pp. 2599-2607. Date of Electronic Publication: 2018 Aug 16.

Abstract: Late-life anxiety has been associated with increased progression from normal cognition to amnestic MCI, suggesting that anxiety may be a neuropsychiatric symptom of Alzheimer's disease (AD) pathological changes and a possible marker of anatomical progr...

Biopolymer-coated gold nanoparticles inhibit human insulin amyloid fibrillation.

Publication Type: Academic Journal

Source(s): Scientific reports [Sci Rep] 2020 May 12; Vol. 10 (1), pp. 7862. Date of Electronic Publication: 2020 May 12.

Abstract: Deposits of protein misfolding and/or aggregates are a pathological hallmark of amyloid-related diseases. For instance, insulin amyloid fibril deposits have been observed in patients with insulin-dependent diabetes mellitus after insulin administration...

99m Technetium pyrophosphate scintigraphy with cadmium zinc telluride cameras is a highly sensitive and specific imaging modality to diagnose transthyretin cardiac amyloidosis.

Publication Type: Academic Journal

Source(s): Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology [J Nucl Cardiol] 2020 Apr; Vol. 27 (2), pp. 371-380. Date of Electronic Publication: 2019 Aug 28.

Abstract: Background: Transthyretin cardiac amyloidosis (ATTR) is a rare, but underdiagnosed, cardiomyopathy. Traditionally diagnosed invasively, ATTR can be diagnosed with non-invasive 99m Technetium pyrophosphate ( 99m Tc-PYP) planar scintigraphy. Non-planar i...

Formation of cytotoxic transthyretin is not dependent on inter-molecular disulphide bridges commonly found within the amyloid form.

Publication Type: Academic Journal

Source(s): Amyloid. Dec2008, Vol. 15 Issue 4, p240-245. 6p. 1 Diagram, 2 Graphs.

Abstract: Familial amyloidotic polyneuropathy (FAP) is linked to destabilising point mutations in the human plasma protein transthyretin (TTR). Consistent with similar amyloid disorders, low molecular weight TTR oligomers have been shown to exert the major cytot...

Lichen amyloidosis.

Publication Type: Academic Journal

Source(s): Dermatology Review / Przeglad Dermatologiczny. 2023, Vol. 110 Issue 1, p37-42. 6p.

Abstract: Wprowadzenie: Liszaj amyloidowy jest najczęstszą formą pierwotnej zlokalizowanej amyloidozy skóry. W typowym obrazie klinicznym widoczne są hiperkeratotyczne grudki na powierzchni wyprostnej kończyn dolnych. W badaniu histopatologicznym stwierdza się o...