Advanced Search Results For "inter-"
Probe-target hybridization depends on spatial uniformity of initial concentration condition across large-format chips.
Publication Type: Academic Journal
Source(s): Scientific reports [Sci Rep] 2020 May 29; Vol. 10 (1), pp. 8768. Date of Electronic Publication: 2020 May 29.
Abstract: Diverse assays spanning from immunohistochemistry (IHC), to microarrays (protein, DNA), to high-throughput screens rely on probe-target hybridization to detect analytes. These large-format 'chips' array numerous hybridization sites across centimeter-sc...
NEW INTER-RELATIONSHIP OF ABIETIC ACID AND AGATHIC ACID.
Publication Type: Academic Journal
Source(s): Chemical & pharmaceutical bulletin [Chem Pharm Bull (Tokyo)] 1963 Oct; Vol. 11, pp. 1328-31.
[CHEMICAL REVIEW OF INDOLE DERIVATIVES OF PHARMACODYNAMIC OR THERAPEUTIC IMPORTANCE].
Publication Type: Academic Journal
Source(s): Il Farmaco; edizione scientifica [Farmaco Sci] 1964 Aug; Vol. 19, pp. 703-25.
A Simplified Model Structure for Compression Characterization of Pharmaceutical Tablets.
Publication Type: Academic Journal
Source(s): Journal of pharmaceutical sciences [J Pharm Sci] 2022 Nov; Vol. 111 (11), pp. 3088-3095. Date of Electronic Publication: 2022 Jul 12.
Abstract: Despite, or maybe because of, many shortcomings, Heckel's equation is by far the most investigated compressibility model for decades. The somewhat overlooked Gurnham equation is proposed as a more stable and better fitting compressibility model. Combin...
Estimating the variability in fraction absorbed as a paradigm for informing formulation development in early clinical drug development.
Publication Type: Academic Journal
Source(s): European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2016 Jun 30; Vol. 89, pp. 50-60. Date of Electronic Publication: 2016 Apr 09.
Abstract: Purpose: Inter-subject variability in oral drug absorption is usually reported using bioavailability, which has the components: fraction absorbed (fa), fraction passing the gut wall (fg) and fraction escaping hepatic metabolism (fh). In this study, we ...
Ascertain a minimum coating thickness for acid protection of enteric coatings by means of optical coherence tomography.
Publication Type: Academic Journal
Source(s): International journal of pharmaceutics [Int J Pharm] 2022 Apr 25; Vol. 618, pp. 121680. Date of Electronic Publication: 2022 Mar 18.
Abstract: Enteric coatings are designed to protect active pharmaceutical ingredients (APIs) against untimely release in the stomach. Acid protection of such coatings depends on the coating layer thickness and integrity, which must be determined in an accurate an...
Formulation pre-screening of inhalation powders using computational atom-atom systematic search method.
Publication Type: Academic Journal
Source(s): Molecular pharmaceutics [Mol Pharm] 2015 Jan 05; Vol. 12 (1), pp. 18-33. Date of Electronic Publication: 2014 Nov 24.
Abstract: The synthonic modeling approach provides a molecule-centered understanding of the surface properties of crystals. It has been applied extensively to understand crystallization processes. This study aimed to investigate the functional relevance of synth...
Robust method optimization strategy-a useful tool for method transfer: the case of SFC.
Publication Type: Academic Journal
Source(s): Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2014 Jan; Vol. 88, pp. 519-24. Date of Electronic Publication: 2013 Oct 12.
Abstract: The concept of Quality by Design (QbD) is now well established in pharmaceutical industry and should be applied to the development of any analytical methods. In this context, the key concept of Design Space (DS) was introduced in the field of analytica...
PIIKA 2.5: Enhanced quality control of peptide microarrays for kinome analysis.
Publication Type: Academic Journal
Source(s): PloS one [PLoS One] 2021 Sep 10; Vol. 16 (9), pp. e0257232. Date of Electronic Publication: 2021 Sep 10 (Print Publication: 2021).
Abstract: Peptide microarrays consisting of defined phosphorylation target sites are an effective approach for high throughput analysis of cellular kinase (kinome) activity. Kinome peptide arrays are highly customizable and do not require species-specific reagen...
Classification of cancer types by measuring variants of host response proteins using SELDI serum assays.
Publication Type: Academic Journal
Source(s): International journal of cancer [Int J Cancer] 2005 Jul 10; Vol. 115 (5), pp. 783-9.
Abstract: Protein expression profiling has been increasingly used to discover and characterize biomarkers that can be used for diagnostic, prognostic or therapeutic purposes. Most proteomic studies published to date have identified relatively abundant host respo...