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Differences in gut microbial fructoselysine degradation activity between breast-fed and formula-fed infants.
Publication Type: Academic Journal
Source(s): FEMS microbiology ecology [FEMS Microbiol Ecol] 2022 Dec 14; Vol. 99 (1).
Abstract: The Amadori product fructoselysine is formed upon heating of food products and is abundantly present in infant formula while being almost absent in breast milk. The human gut microbiota can degrade fructoselysine for which interindividual differences h...
Inter- and Intraindividual Differences in the Capacity of the Human Intestinal Microbiome in Fecal Slurries to Metabolize Fructoselysine and Carboxymethyllysine.
Publication Type: Academic Journal
Source(s): Journal of agricultural and food chemistry [J Agric Food Chem] 2022 Sep 21; Vol. 70 (37), pp. 11759-11768. Date of Electronic Publication: 2022 Sep 07.
Abstract: The advanced glycation endproduct carboxymethyllysine and its precursor fructoselysine are present in heated, processed food products and are considered potentially hazardous for human health. Upon dietary exposure, they can be degraded by human coloni...
Differences in kinetics and dynamics of endogenous versus exogenous advanced glycation end products (AGEs) and their precursors.
Publication Type: Academic Journal
Source(s): Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2022 Jun; Vol. 164, pp. 112987. Date of Electronic Publication: 2022 Apr 06.
Abstract: Advanced glycation end products (AGEs) and their precursors, referred to as glycation products, are a heterogenous group of compounds being associated with adverse health effects. They are formed endogenously and in exogenous sources including food. Th...
The Influence of Intracellular Glutathione Levels on the Induction of Nrf2-Mediated Gene Expression by α-Dicarbonyl Precursors of Advanced Glycation End Products.
Publication Type: Academic Journal
Source(s): Nutrients [Nutrients] 2022 Mar 24; Vol. 14 (7). Date of Electronic Publication: 2022 Mar 24.
Abstract: α-Dicarbonyl compounds, particularly methylglyoxal (MGO), glyoxal (GO), and 3-deoxyglucosone (3-DG), are highly reactive precursors for the formation of advanced glycation end products (AGEs). They are formed in vivo and during food processing. This st...
Dietary advanced glycation endproducts (AGEs) increase their concentration in plasma and tissues, result in inflammation and modulate gut microbial composition in mice; evidence for reversibility.
Publication Type: Academic Journal
Source(s): Food research international (Ottawa, Ont.) [Food Res Int] 2021 Sep; Vol. 147, pp. 110547. Date of Electronic Publication: 2021 Jun 18.
Abstract: Scope: Dietary advanced glycation endproducts (AGEs) are associated with negative biological effects, possibly due to accumulation in plasma and tissues and through modulation of inflammation and gut microbiota. Whether these biological consequences ar...
An in vitro model for microbial fructoselysine degradation shows substantial interindividual differences in metabolic capacities of human fecal slurries.
Publication Type: Academic Journal
Source(s): Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2021 Apr; Vol. 72, pp. 105078. Date of Electronic Publication: 2021 Jan 08.
Abstract: Fructoselysine is formed upon heating during processing of food products, and being a key intermediate in advanced glycation end product formation considered to be potentially hazardous to human health. Human gut microbes can degrade fructoselysine to ...