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Advanced Search Results For "��ora, Hakan"

1 - 10 of 19 results for
 "��ora, Hakan"
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Prevalence of germline pathogenic variants in 22 cancer susceptibility genes in Swedish pediatric cancer patients

Publication Type:Academic Journal

Source(s):Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Abstract:Abstract Up to 10% of pediatric cancer patients harbor pathogenic germline variants in one or more cancer susceptibility genes. A recent study from the US reported pathogenic variants in 22 out of 60 analyzed autosomal dominant cancer susceptibility ge...

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Predominance of girls with cancer in families with multiple childhood cancer cases

Publication Type:Academic Journal

Source(s):BMC Cancer, Vol 17, Iss 1, Pp 1-9 (2017)

Abstract:Abstract Background Recent studies indicate that one of four childhood cancers can be attributed to hereditary genetic abnormalities. Methods The Lund Childhood Cancer Genetic study includes newly diagnosed childhood cancer patients as well as childhoo...

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Prevalence of germline pathogenic variants in 22 cancer susceptibility genes in Swedish pediatric cancer patients.

Publication Type:Academic Journal

Source(s):Scientific Reports; 3/5/2021, Vol. 11 Issue 1, p1-10, 10p

Abstract:Copyright of Scientific Reports is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or ...

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Increased Cancer Risk in Families with Pediatric Cancer Is Associated with Gender, Age, Diagnosis, and Degree of Relation to the Child.

Publication Type:Academic Journal

Source(s):Cancer Epidemiology, Biomarkers & Prevention; Nov2020, Vol. 29 Issue 11, p2171-2179, 9p

Abstract:Copyright of Cancer Epidemiology, Biomarkers & Prevention is the property of American Association for Cancer Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written ...

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Individual patient risk stratification of high-risk neuroblastomas using a two-gene score suited for clinical use.

Publication Type:Academic Journal

Source(s):International Journal of Cancer; Aug2015, Vol. 137 Issue 4, p868-877, 10p

Abstract:Copyright of International Journal of Cancer is the property of John Wiley & Sons, Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may...

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snoRNPs Regulate Telomerase Activity in Neuroblastoma and Are Associated with Poor Prognosis

Publication Type:Periodical

Source(s):Translational Oncology; August 2013, Vol. 6 Issue: 4 p447,IN6-457,IN6, 454p

Abstract:Amplification of the MYCNoncogene is strongly associated with poor prognosis in neuroblastoma (NB). In addition to MYCNamplification, many studies have focused on identifying patients with a poor prognosis based on gene expression profiling. The majori...

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Hypoxia-induced dedifferentiation in neuroblastoma cells

Publication Type:Academic Journal

Source(s):Cancer Letters. Jul2003, Vol. 197 Issue 1/2, p145. 6p.

Abstract:Hypoxia in solid tumors is associated with aggressive behavior and poor outcome. We recently discovered that hypoxia alters the expression of differentiation marker genes in neuroblastoma cells, in that the tumor cells adjust to the hypoxic environment...

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Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma.

Publication Type:Academic Journal

Source(s):Cancer research [Cancer Res] 2018 Oct 15; Vol. 78 (20), pp. 5958-5969. Date of Electronic Publication: 2018 Aug 28.

Abstract:Patient-derived xenografts (PDX) and the Avatar, a single PDX mirroring an individual patient, are emerging tools in preclinical cancer research. However, the consequences of intratumor heterogeneity for PDX modeling of biomarkers, target identificatio...

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Predominance of girls with cancer in families with multiple childhood cancer cases.

Publication Type:Academic Journal

Source(s):BMC cancer [BMC Cancer] 2017 Dec 19; Vol. 17 (1), pp. 868. Date of Electronic Publication: 2017 Dec 19.

Abstract:Background: Recent studies indicate that one of four childhood cancers can be attributed to hereditary genetic abnormalities.Methods: The Lund Childhood Cancer Genetic study includes newly diagnosed childhood cancer patients as well as childhood cancer...

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Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer.

Publication Type:Academic Journal

Source(s):JAMA [JAMA] 2012 Jan 25; Vol. 307 (4), pp. 382-90.

Abstract:Context: Approximately 10% of women with invasive epithelial ovarian cancer (EOC) carry deleterious germline mutations in BRCA1 or BRCA2. A recent article suggested that BRCA2-related EOC was associated with an improved prognosis, but the effect of BRC...

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