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Advanced Search Results For "Abdel-Aziz, Amal Kamal"

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 "Abdel-Aziz, Amal Kamal"
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A Critical Review of Chloroquine and Hydroxychloroquine as Potential Adjuvant Agents for Treating People with Cancer.

Publication Type: Academic Journal

Source(s): Future Pharmacology; Dec2022, Vol. 2 Issue 4, p431-443, 13p

Abstract: Copyright of Future Pharmacology is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email arti...

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Mechanistic approach of the inhibitory effect of chrysin on inflammatory and apoptotic events implicated in radiation-induced premature ovarian failure: Emphasis on TGF-β/MAPKs signaling pathway

Publication Type: Academic Journal

Source(s): Biomedicine & Pharmacotherapy, Vol 109, Iss , Pp 293-303 (2019)

Abstract: Radiotherapy is one of the most relevant treatment modalities for various types of malignancies. However, it causes premature ovarian failure (POF) and subsequent infertility in women of reproductive age; hence urging the development of effective radio...

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Co-targeting leukemia-initiating cells and leukemia bulk leads to disease eradication

Publication Type: Periodical

Source(s): Leukemia; May 2022, Vol. 36 Issue: 5 p1306-1312, 7p

Abstract: According to a hierarchical model, targeting leukemia-initiating cells (LICs) was speculated to achieve complete remission (CR) or cure. Nonetheless, increasing evidence emphasized the plasticity of differentiated blasts undergoing interconversion into...

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Serum sclerostin and irisin as predictive markers for atherosclerosis in Egyptian type II diabetic female patients: A case control study.

Publication Type: Academic Journal

Source(s): PLoS ONE, Vol 13, Iss 11, p e0206761 (2018)

Abstract: Diabetes mellitus represents a major independent risk factor for developing fatal cardiovascular diseases (CVDs) presumably through accelerating atherosclerosis; the underlying cause of most CVDs. Notably, this relative risk is reported to be higher in...

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From Resistance to Sensitivity: Insights and Implications of Biphasic Modulation of Autophagy by Sunitinib

Publication Type: Academic Journal

Source(s): Frontiers in Pharmacology, Vol 8 (2017)

Abstract: Sunitinib, a multityrosine kinase inhibitor, is currently the standard first-line therapy in metastatic renal cell carcinoma (mRCC) and is also used in treating patients with pancreatic neuroendocrine and imatinib-resistant gastrointestinal stromal tum...

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Tuning mTORC1 activity dictates the response of acute myeloid leukemia to LSD1 inhibition.

Publication Type: Academic Journal

Source(s): Haematologica: The Hematology Journal; Aug2020, Vol. 105 Issue 8, p2105-2117, 13p

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

Publication Type: Academic Journal

Source(s): Autophagy; Jan2021, Vol. 17 Issue 1, p1-382, 382p

Abstract: Copyright of Autophagy is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or emai...

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Discovery of EMD37, a 1,2,4-oxadiazole derivative, as a novel endoplasmic reticulum stress inducer with potent anticancer activity.

Publication Type: Academic Journal

Source(s): Biochemical Pharmacology. Dec2022, Vol. 206, pN.PAG-N.PAG. 1p.

Abstract: [Display omitted] Targeting endoplasmic reticulum (ER) stress presents a promising strategy in cancer therapy. We previously reported a series of 1,2,4-oxadiazole derivatives that induced the degradation of EGFR and c-Met which are implicated in tumori...

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