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Frequency of non-thyroidal illness syndrome in pediatric patients with sepsis and septic shock
Publication Type: Academic Journal
Source(s): Egyptian Pediatric Association Gazette, Vol 70, Iss 1, Pp 1-8 (2022)
Abstract: Abstract Background Non-thyroidal illness syndrome (NTIS) is considered when patients demonstrate altered thyroid hormones and is frequently seen in patients with sepsis and septic shock. Levels keep affected with disease progression and usually get no...
A Versatile Biomimic Nanotemplating Fluidic Assay for Multiplex Quantitative Monitoring of Viral Respiratory Infections and Immune Responses in Saliva and Blood
Publication Type: Academic Journal
Source(s): Advanced Science, Vol 9, Iss 33, Pp n/a-n/a (2022)
Abstract: Abstract The last pandemic exposed critical gaps in monitoring and mitigating the spread of viral respiratory infections at the point‐of‐need. A cost‐effective multiplexed fluidic device (NFluidEX), as a home‐test kit analogous to a glucometer, that us...
Network Pharmacology of Ginseng (Part III): Antitumor Potential of a Fixed Combination of Red Ginseng and Red Sage as Determined by Transcriptomics
Publication Type: Academic Journal
Source(s): Pharmaceuticals, Vol 15, Iss 1345, p 1345 (2022)
Abstract: Background: This study aimed to assess the effect of a fixed combination of Red Ginseng and Red Sage (RG–RS) on the gene expression of neuronal cells to evaluate the potential impacts on cellular functions and predict its relevance in the treatment of ...
Potential Coronaviral Inhibitors of the Nucleocapsid Protein Identified In Silico and In Vitro from a Large Natural Product Library
Publication Type: Academic Journal
Source(s): Pharmaceuticals, Vol 15, Iss 1046, p 1046 (2022)
Abstract: The nucleocapsid protein (NP) is one of the main proteins out of four structural proteins of coronaviruses including the severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, discovered in 2019. NP packages the viral RNA during virus assembly an...
In Silico and In Vitro Identification of Pan-Coronaviral Main Protease Inhibitors from a Large Natural Product Library
Publication Type: Academic Journal
Source(s): Pharmaceuticals, Vol 15, Iss 308, p 308 (2022)
Abstract: The main protease (Mpro or 3CLpro) in coronaviruses represents a promising specific drug target as it is essential for the cleavage of the virus polypeptide and has a unique cleavage site that does not exist in human host proteases. In this study, we e...
Network Pharmacology of Ginseng (Part III): Antitumor Potential of a Fixed Combination of Red Ginseng and Red Sage as Determined by Transcriptomics.
Publication Type: Academic Journal
Source(s): Pharmaceuticals (14248247); Nov2022, Vol. 15 Issue 11, p1345, 15p
Abstract: Copyright of Pharmaceuticals (14248247) is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or ema...
Accuracy assessment for Landsat 8 thermal bands in measuring sea surface temperature over Kuwait and North West Arabian Gulf.
Publication Type: Academic Journal
Source(s): Kuwait Journal of Science. 2022, Vol. 49 Issue 1, p1-13. 13p.
Abstract: Studying physical oceanography is one of the important fields of remote sensing applications. Previously, the thermal mapping of seas and oceans relied on primitive methods, such as the use of sensors installed on buoys, extracting contour lines, and d...
Network Pharmacology of Red Ginseng (Part I): Effects of Ginsenoside Rg5 at Physiological and Sub-Physiological Concentrations
Publication Type: Academic Journal
Source(s): Pharmaceuticals, Vol 14, Iss 999, p 999 (2021)
Abstract: Numerous in vitro studies on isolated cells have been conducted to uncover the molecular mechanisms of action of Panax ginseng Meyer root extracts and purified ginsenosides. However, the concentrations of ginsenosides and the extracts used in these stu...
Network Pharmacology of Ginseng (Part II): The Differential Effects of Red Ginseng and Ginsenoside Rg5 in Cancer and Heart Diseases as Determined by Transcriptomics
Publication Type: Academic Journal
Source(s): Pharmaceuticals, Vol 14, Iss 1010, p 1010 (2021)
Abstract: Panax ginseng C.A.Mey. is an adaptogenic plant traditionally used to enhance mental and physical capacities in cases of weakness, exhaustion, tiredness, or loss of concentration, and during recovery. According to ancient records, red ginseng root prepa...
MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate
Publication Type: Academic Journal
Source(s): Acta Pharmaceutica Sinica B, Vol 9, Iss 5, Pp 1021-1034 (2019)
Abstract: Polo-like kinase (PLK1) has been identified as a potential target for cancer treatment. Although a number of small molecules have been investigated as PLK1 inhibitors, many of which showed limited selectivity. PLK1 harbors a regulatory domain, the Polo...