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Factors determining ultra-short-term survival and the commencement of active treatment in high-grade serous ovarian cancer: a case comparison study
Publication Type: Academic Journal
Source(s): BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract: Abstract Background Despite improvements in median survival some patients with advanced ovarian cancer die within 100 days of diagnosis; the reasons for which remain poorly understood. Here we investigate if ultra short-term survival can be explained b...
Response: Commentary: Underestimating the Challenges of Avoiding a Ghastly Future
Publication Type: Academic Journal
Source(s): Frontiers in Conservation Science, Vol 2 (2021)
Improving Situational Awareness in the Arctic Ocean
Publication Type: Academic Journal
Source(s): Frontiers in Marine Science, Vol 7 (2020)
Abstract: To successfully operate in a harsh environment like the Arctic Ocean, one must be able to understand and predict how that environment will evolve over different spatial and temporal scales. This is particularly challenging given the on-going and signif...
Correction to: Factors determining ultra-short-term survival and the commencement of active treatment in high-grade serous ovarian cancer: a case comparison study
Publication Type: Academic Journal
Source(s): BMC Cancer, Vol 21, Iss 1, Pp 1-1 (2021)
Nurses who work in rural and remote communities in Canada: a national survey
Publication Type: Academic Journal
Source(s): Human Resources for Health, Vol 15, Iss 1, Pp 1-11 (2017)
Abstract: Abstract Background In Canada, as in other parts of the world, there is geographic maldistribution of the nursing workforce, and insufficient attention is paid to the strengths and needs of those providing care in rural and remote settings. In order to...
A Molecular Model for Predicting Overall Survival in Patients with Metastatic Clear Cell Renal Carcinoma: Results from CALGB 90206 (Alliance)
Publication Type: Academic Journal
Source(s): EBioMedicine, Vol 2, Iss 11, Pp 1814-1820 (2015)
Abstract: Background: Prognosis associated with metastatic renal cell carcinoma (mRCC) can vary widely. Methods: This study used pretreatment nephrectomy specimens from a randomized phase III trial. Expression levels of candidate genes were determined from archi...
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
Publication Type: Academic Journal
Source(s): Genome Biology, Vol 23, Iss 1, Pp 1-42 (2022)
Abstract: Abstract Background Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings an...
Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers
Publication Type: Academic Journal
Source(s): Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Abstract: The risk of germline copy number variants (CNVs) in BRCA1 and BRCA2 pathogenic variant carriers in breast cancer is assessed, with CNVs overlapping SULT1A1 decreasing breast cancer risk in BRCA1 carriers.
Paediatric COVID-19 mortality: a database analysis of the impact of health resource disparity
Publication Type: Academic Journal
Source(s): BMJ Paediatrics Open, Vol 6, Iss 1 (2022)
Abstract: Background The impact of the COVID-19 pandemic on paediatric populations varied between high-income countries (HICs) versus low-income to middle-income countries (LMICs). We sought to investigate differences in paediatric clinical outcomes and identify...
Modulation of the Association Between Age and Death by Risk Factor Burden in Critically Ill Patients With COVID-19
Publication Type: Academic Journal
Source(s): Critical Care Explorations, Vol 4, Iss 9, p e0755 (2022)
Abstract: OBJECTIVES:. Older age is a key risk factor for adverse outcomes in critically ill patients with COVID-19. However, few studies have investigated whether preexisting comorbidities and acute physiologic ICU factors modify the association between age and...