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Glutathione S-transferases GSTM1 and GSTT1 polymorphisms and asbestosis.
Publication Type: Academic Journal
Source(s): Journal of Occupational & Environmental Medicine; Jun2007, Vol. 49 Issue 6, p667-671, 5p
Manganese Superoxide Dismutase and Catalase Genetic Polymorphisms and Risk of Asbestosis.
Publication Type: Academic Journal
Source(s): Epidemiology; Nov2008 Supplement, Vol. 19, pS80-S81, 2p
The influence of gene-gene and gene-environment interactions on the risk of asbestosis.
Publication Type: Academic Journal
Source(s): BioMed Research International; 2013, Vol. 2013, p405743-405743, 1p
Abstract: Copyright of BioMed Research International is the property of Hindawi Limited and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, do...
Discovery of N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an Agonist of the α7 Nicotinic Acetylcholine Receptor, for the Potential Treatment of Cognitive Deficits in Schizophrenia:  Synthesis and Structure−Activity Relationship
Publication Type: Periodical
Source(s): Journal of Medicinal Chemistry; July 2006, Vol. 49 Issue: 14 p4425-4436, 12p
Abstract: N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide (14, PHA-543,613), a novel agonist of the α7 neuronal nicotinic acetylcholine receptor (α7 nAChR), has been identified as a potential treatment of cognitive deficits in schizophrenia...
Cerebrospinal Fluid Biomarkers for Alzheimer's Disease: A View of the Regulatory Science Qualification Landscape from the Coalition Against Major Diseases CSF Biomarker Team.
Publication Type: Academic Journal
Source(s): Journal of Alzheimer's Disease; 2017, Vol. 55 Issue 1, p19-35, 17p
Abstract: Copyright of Journal of Alzheimer's Disease is the property of IOS Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, downloa...
Antagonism of CRF2 receptors produces anxiolytic behavior in animal models of anxiety
Publication Type: Periodical
Source(s): Brain Research; 2001, Vol. 902 Issue: 2 p135-142, 8p
Cerebrospinal Fluid Biomarkers for Alzheimer's Disease: A View of the Regulatory Science Qualification Landscape from the Coalition Against Major Diseases CSF Biomarker Team.
Publication Type: Academic Journal
Source(s): Journal of Alzheimer's Disease; 2017, Vol. 55 Issue 1, p19-35, 17p
Abstract: Copyright of Journal of Alzheimer's Disease is the property of IOS Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, downloa...
Presenilin-1 and -2 Are Molecular Targets for γ-Secretase Inhibitors*
Publication Type: Periodical
Source(s): Journal of Biological Chemistry; November 2000, Vol. 275 Issue: 44 p34086-34091, 6p
Abstract: Presenilins are integral membrane protein involved in the production of amyloid β-protein. Mutations of the presenilin-1 and -2 gene are associated with familial Alzheimer's disease and are thought to alter γ-secretase cleavage of the β-amyloid precurs...
ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective antinociceptive agent acting via neuronal nicotinic acetylcholine receptors: II. In vivo characterization.
Publication Type: Periodical
Source(s): The Journal of Pharmacology and Experimental Therapeutics; May 1998, Vol. 285 Issue: 2 p787-94, 8p
Abstract: The antinociceptive effects of ABT-594, a novel nicotinic acetylcholine receptor (nAChR) ligand, were examined in rats in models of acute thermal (hot box) and persistent chemical (formalin test) pain. Also, the effects of ABT-594 treatment on motor fu...