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Advanced Search Results For "BUCKLEY, BRUCE"

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 "BUCKLEY, BRUCE"
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Using large climate model ensembles to assess historical and future tropical cyclone activity along the Australian east coast

Publication Type: Academic Journal

Source(s): Weather and Climate Extremes, Vol 38, Iss , Pp 100507- (2022)

Abstract: Assessing regional changes in tropical cyclones (TCs) and their future impacts are challenging given the short historical record and limited sample size of these extreme events. To address this, we use large climate model ensembles to increase sample s...

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Potential methylation-regulated genes and pathways in hepatocellular neoplasm, not otherwise specified

Publication Type: Academic Journal

Source(s): Frontiers in Oncology, Vol 12 (2022)

Abstract: Background and AimsThe molecular basis of hepatocellular neoplasm, not otherwise specified (HCN-NOS) is unknown. We aimed to identify gene expression patterns, potential methylation-regulated genes and pathways that characterize the tumor, and its poss...

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Feasibility of reporting results of large randomised controlled trials to participants: experience from the Fluoxetine Or Control Under Supervision (FOCUS) trial

Publication Type: Academic Journal

Source(s): BMJ Open, Vol 10, Iss 11 (2020)

Abstract: Objectives Informing research participants of the results of studies in which they took part is viewed as an ethical imperative. However, there is little guidance in the literature about how to do this. The Fluoxetine Or Control Under Supervision trial...

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Arthritis prevention in the pre-clinical phase of RA with abatacept (the APIPPRA study): a multi-centre, randomised, double-blind, parallel-group, placebo-controlled clinical trial protocol

Publication Type: Academic Journal

Source(s): Trials, Vol 20, Iss 1, Pp 1-15 (2019)

Abstract: Abstract Trial design We present a study protocol for a multi-centre, randomised, double-blind, parallel-group, placebo-controlled trial that seeks to test the feasibility, acceptability and effectiveness of a 52-week period of treatment with the first...

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Irgm1-deficiency leads to myeloid dysfunction in colon lamina propria and susceptibility to the intestinal pathogen Citrobacter rodentium.

Publication Type: Academic Journal

Source(s): PLoS Pathogens, Vol 16, Iss 5, p e1008553 (2020)

Abstract: IRGM and its mouse orthologue Irgm1 are dynamin-like proteins that regulate vesicular remodeling, intracellular microbial killing, and pathogen immunity. IRGM dysfunction is linked to inflammatory bowel disease (IBD), and while it is thought that defec...

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Adolescent follow-up in the Health Outcomes and Measures of the Environment (HOME) Study: cohort profile

Publication Type: Academic Journal

Source(s): BMJ Open, Vol 10, Iss 5 (2020)

Abstract: Purpose Environmental chemical exposures may adversely affect an array of adolescent health outcomes. Thus, we used the Health Outcomes and Measures of the Environment (HOME) study, a prospective cohort that recruited pregnant women and conducted longi...

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PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)

Abstract: Abnormal PR interval duration is associated with risk for atrial fibrillation and heart block. Here, van Setten et al. identify 44 PR interval loci in a genome-wide association study of over 92,000 individuals and find genetic overlap with QRS duration...

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Submaximal Exercise Testing in Cardiovascular Rehabilitation Settings (BEST Study)

Publication Type: Academic Journal

Source(s): Frontiers in Physiology, Vol 10 (2020)

Abstract: BackgroundThis study compared changes in measured versus predicted peak aerobic power (V̇O2peak) following cardiovascular rehabilitation (CR). Peak cardiopulmonary exercise testing (CPET) results were compared to four V̇O2peak estimation methods: the s...

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Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 8, Iss 1, Pp 1-19 (2017)

Abstract: Genome-wide association studies (GWAS) have become a key tool to discover genetic markers for complex traits; however, environmental factors that interact with genes are rarely considered. Here, the authors conduct a GWAS of obesity traits, and find th...

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Physically-based landfalling tropical cyclone scenarios in support of risk assessment

Publication Type: Academic Journal

Source(s): Weather and Climate Extremes, Vol 26, Iss , Pp - (2019)

Abstract: Populations and property values are increasing in tropical cyclone prone regions, driving up repair and replacement costs following a tropical cyclone impact. Climate change influences on tropical cyclones and sea levels will only exacerbate these rise...

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