Advanced Search Results For "Barbier, Christophe"
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Deciphering the mechanism of action of VP343, an antileishmanial drug candidate, in Leishmania infantum
Publication Type: Academic Journal
Source(s): iScience, Vol 26, Iss 11, Pp 108144- (2023)
Abstract: Summary: Antileishmanial chemotherapy is currently limited due to severe toxic side effects and drug resistance. Hence, new antileishmanial compounds based on alternative approaches, mainly to avoid the emergence of drug resistance, are needed. The pre...
Hornification in Commercial Chemical Pulps: Dependence on Water Removal and Hornification Mechanisms
Publication Type: Academic Journal
Source(s): BioResources, Vol 18, Iss 2, Pp 3856-3869 (2023)
Abstract: Understanding cellulose hornification provides crucial information regarding drying of pulp, paper, and other cellulosic materials as well as recycling them. By measuring drainage, fiber width, and water retention value of hardwood and softwood pulps b...
Daily practices in chemotherapy for advanced gastric or gastroesophageal junction adenocarcinoma: METESTOMAC French prospective cohort
Publication Type: Academic Journal
Source(s): Cancer Medicine, Vol 12, Iss 5, Pp 5341-5351 (2023)
Abstract: Abstract Background Around 50% of gastric cancers are diagnosed at an advanced stage. Several chemotherapy regimens are now internationally validated. Few data are available on the routine daily management of advanced gastric or gastroesophageal juncti...
Evaluation of kernel low-rank compressed sensing in preclinical diffusion magnetic resonance imaging
Publication Type: Academic Journal
Source(s): Frontiers in Neuroscience, Vol 17 (2023)
Abstract: Compressed sensing (CS) is widely used to accelerate clinical diffusion MRI acquisitions, but it is not widely used in preclinical settings yet. In this study, we optimized and compared several CS reconstruction methods for diffusion imaging. Different...
Rapid rEcognition of COrticosteRoiD resistant or sensitive Sepsis (RECORDS): study protocol for a multicentre, placebo-controlled, biomarker-guided, adaptive Bayesian design basket trial
Publication Type: Academic Journal
Source(s): BMJ Open, Vol 13, Iss 3 (2023)
Abstract: Introduction Corticosteroids affect variably survival in sepsis trials, suggesting heterogeneity in patients’ response to corticosteroids. The RECORDS (Rapid rEcognition of COrticosteRoiD resistant or sensitive Sepsis) trial aimed at defining endotypes...
Women and health professionals’ perspectives on a conditional cash transfer programme to improve pregnancy follow-up: a qualitative analysis of the NAITRE randomised controlled study
Publication Type: Academic Journal
Source(s): BMJ Open, Vol 13, Iss 3 (2023)
Abstract: Objectives Women of low socioeconomic status have been described as having suboptimal prenatal care, which in turn has been associated with poor pregnancy outcomes. Many types of conditional cash transfer (CCT) programmes have been developed, including...
Inevitability of disease recurrence after liver transplantation for NAFLD cirrhosis
Publication Type: Academic Journal
Source(s): JHEP Reports, Vol 5, Iss 3, Pp 100668- (2023)
Abstract: Background & Aims: Liver transplantation (LT) is the only available treatment for end-stage non-alcoholic fatty liver disease (NAFLD) (related decompensated cirrhosis and/or hepatocellular carcinoma). The aim of our study was to evaluate the risk of di...
AFP score and metroticket 2.0 perform similarly and could be used in a 'within-ALL' clinical decision tool
Publication Type: Academic Journal
Source(s): JHEP Reports, Vol 5, Iss 2, Pp 100644- (2023)
Abstract: Background & Aims: Two recently developed composite models, the alpha-fetoprotein (AFP) score and Metroticket 2.0, could be used to select patients with hepatocellular carcinoma (HCC) who are candidates for liver transplantation (LT). The aim of this s...
Risk Factors of AKI in Acute Respiratory Distress Syndrome: A Time-Dependent Competing Risk Analysis on Severe COVID-19 Patients
Publication Type: Academic Journal
Source(s): Canadian Journal of Kidney Health and Disease, Vol 10 (2023)
Abstract: Introduction: Acute kidney injury (AKI) is frequently observed in patients with COVID-19 admitted to intensive care units (ICUs). Observational studies suggest that cardiovascular comorbidities and mechanical ventilation (MV) are the most important ris...
Surgical Treatment of Juvenile Idiopathic Arthritis in the Era of Novel Drug Therapies
Publication Type: Academic Journal
Source(s): Journal of Clinical Medicine, Vol 12, Iss 10, p 3402 (2023)
Abstract: Juvenile idiopathic arthritis is the most common chronic rheumatic disease encountered in children under the age of sixteen and causes significant impairments in daily life. Over the last two decades, the introduction of new drug treatments (including ...