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Advanced Search Results For "Becher, David A"

1 - 10 of 311 results for
 "Becher, David A"
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Genome-wide interaction analysis of menopausal hormone therapy use and breast cancer risk among 62,370 women

Publication Type:Academic Journal

Source(s):Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)

Abstract:Abstract Use of menopausal hormone therapy (MHT) is associated with increased risk for breast cancer. However, the relevant mechanisms and its interaction with genetic variants are not fully understood. We conducted a genome-wide interaction analysis b...

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Coherence of a charge stabilised tin-vacancy spin in diamond

Publication Type:Academic Journal

Source(s):npj Quantum Information, Vol 8, Iss 1, Pp 1-9 (2022)

Abstract:Abstract Quantum information processing (QIP) with solid state spin qubits strongly depends on the efficient initialisation of the qubit’s desired charge state. While the negatively charged tin-vacancy (SnV−) centre in diamond has emerged as an excelle...

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Unravelling the sex-specific diversity and functions of adrenal gland macrophages

Publication Type:Academic Journal

Source(s):Cell Reports, Vol 39, Iss 11, Pp 110949- (2022)

Abstract:Summary: Despite the ubiquitous function of macrophages across the body, the diversity, origin, and function of adrenal gland macrophages remain largely unknown. We define the heterogeneity of adrenal gland immune cells using single-cell RNA sequencing...

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Study design and rationale of the pAtients pResenTing with cOngenital heaRt dIseAse Register (ARTORIA‐R)

Publication Type:Academic Journal

Source(s):ESC Heart Failure, Vol 8, Iss 6, Pp 5542-5550 (2021)

Abstract:Abstract Aim Due to improved therapy in childhood, many patients with congenital heart disease reach adulthood and are termed adults with congenital heart disease (ACHD). ACHD often develop heart failure (HF) as a consequence of initial palliative surg...

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Brown adipose tissue monocytes support tissue expansion

Publication Type:Academic Journal

Source(s):Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)

Abstract:Adipose tissue is composed of a number of adipocytes and a number of other cells including immune cells. Here the authors use single-cell sequencing of murine brown adipose tissue immune cells and describe multiple macrophage and monocyte subsets and s...

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Creditor Control of Corporate Acquisitions.

Publication Type:Academic Journal

Source(s):Review of Financial Studies; Apr2022, Vol. 35 Issue 4, p1897-1932, 36p

Abstract:Copyright of Review of Financial Studies is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users m...

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Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis

Publication Type:Academic Journal

Source(s):Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

Abstract:Abstract Breast cancer metastasis accounts for most of the deaths from breast cancer. Identification of germline variants associated with survival in aggressive types of breast cancer may inform understanding of breast cancer progression and assist tre...

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Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment

Publication Type:Academic Journal

Source(s):Breast Cancer Research, Vol 23, Iss 1, Pp 1-18 (2021)

Abstract:Abstract Background Given the high heterogeneity among breast tumors, associations between common germline genetic variants and survival that may exist within specific subgroups could go undetected in an unstratified set of breast cancer patients. Meth...

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A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Publication Type:Academic Journal

Source(s):Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)

Abstract:Breast cancer risk for BRCA1/BRCA2 mutation carriers varies depending on other genetic factors. Here, the authors perform a case-only genome-wide association study and highlight novel loci associated with breast cancer risk for BRCA1/BRCA2 mutation car...

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Using Real‐World Data to Guide Ustekinumab Dosing Strategies for Psoriasis: A Prospective Pharmacokinetic‐Pharmacodynamic Study

Publication Type:Academic Journal

Source(s):Clinical and Translational Science, Vol 13, Iss 2, Pp 400-409 (2020)

Abstract:Variation in response to biologic therapy for inflammatory diseases, such as psoriasis, is partly driven by variation in drug exposure. Real‐world psoriasis data were used to develop a pharmacokinetic/pharmacodynamic (PK/PD) model for the first‐line th...

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