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Preoperative robotic radiosurgery for early breast cancer: Results of the phase II ROCK trial (NCT03520894)
Publication Type: Academic Journal
Source(s): Clinical and Translational Radiation Oncology, Vol 37, Iss , Pp 94-100 (2022)
Abstract: Background and purpose: Preoperative partial breast irradiation (PBI) has got the advantage of treating a well-defined target. We report the results of the phase II ROCK trial (NCT03520894), enrolling early breast cancer (BC) patients treated with preo...
Tumors carrying BRAF-mutations over-express NAMPT that is genetically amplified and possesses oncogenic properties
Publication Type: Academic Journal
Source(s): Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract: Abstract Background Nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme in nicotinamide adenine dinucleotide (NAD) biosynthesis, is up-regulated in several cancers, including metastatic melanoma (MM). The BRAF oncogene is mutated i...
Which clinical, radiological, histological, and molecular parameters are associated with the absence of enhancement of known breast cancers with Contrast Enhanced Digital Mammography (CEDM)?
Publication Type: Academic Journal
Source(s): Breast, Vol 54, Iss , Pp 15-24 (2020)
Abstract: Background: CEDM has demonstrated a diagnostic performance similar to MRI and could have similar limitations in breast cancer (BC) detection. Purpose: The aim of our study was to systematically analyze the characteristics of the lesions with the absenc...
Triple-Negative Breast Cancer Histological Subtypes with a Favourable Prognosis
Publication Type: Academic Journal
Source(s): Cancers, Vol 13, Iss 5694, p 5694 (2021)
Abstract: Triple-negative breast cancers (TNBC), as a group of tumours, have a worse prognosis than stage-matched non-TNBC and lack the benefits of routinely available targeted therapy. However, TNBC is a heterogeneous group of neoplasms, which includes some spe...
A Fit to the Available e+e− → Λc+Λ¯c− Cross Section Data Nearby Production Threshold by Means of a Strong Correction to the Coulomb Enhancement Factor
Publication Type: Academic Journal
Source(s): Universe, Vol 7, Iss 436, p 436 (2021)
Abstract: There are two available sets of data on the e+e−→Λc+Λ¯c− cross section at energies close to the production threshold, collected by the Belle and by the BESIII Collaborations. The measurement of the former, performed by means of the initial state radiat...
Notulae to the Italian flora of algae, bryophytes, fungi and lichens: 8
Publication Type: Academic Journal
Source(s): Italian Botanist, Vol 8, Iss , Pp 47-62 (2019)
Abstract: In this contribution, new data concerning algae, bryophytes, fungi, and lichens of the Italian flora are presented. It includes new records and confirmations for the algae genus Chara, the bryophyte genera Homalia, Mannia, and Tortella, the fungal gene...
Transcriptome of Male Breast Cancer Matched with Germline Profiling Reveals Novel Molecular Subtypes with Possible Clinical Relevance
Publication Type: Academic Journal
Source(s): Cancers, Vol 13, Iss 4515, p 4515 (2021)
Abstract: Male breast cancer (MBC) is a rare and understudied disease compared with female BC. About 15% of MBCs are associated with germline mutation in BC susceptibility genes, mainly BRCA1/2 and PALB2. Hereditary MBCs are likely to represent a subgroup of tum...
Intra-Tumour Heterogeneity Is One of the Main Sources of Inter-Observer Variation in Scoring Stromal Tumour Infiltrating Lymphocytes in Triple Negative Breast Cancer
Publication Type: Academic Journal
Source(s): Cancers, Vol 13, Iss 4410, p 4410 (2021)
Abstract: Stromal tumour infiltrating lymphocytes (sTILs) are a strong prognostic marker in triple negative breast cancer (TNBC). Consistency scoring sTILs is good and was excellent when an internet-based scoring aid developed by the TIL-WG was used to score cas...
Evaluation of CYP17A1 and CYP1B1 polymorphisms in male breast cancer risk
Publication Type: Academic Journal
Source(s): Endocrine Connections, Vol 8, Iss 8, Pp 1224-1229 (2019)
Abstract: Breast cancer in men is a rare and still poorly characterized disease. Inherited mutations in BRCA1, BRCA2 and PALB2 genes, as well as common polymorphisms, play a role in male breast cancer genetic predisposition. Male breast cancer is considered a ho...
Immunohistochemical Evaluation of FGD3 Expression: A New Strong Prognostic Factor in Invasive Breast Cancer
Publication Type: Academic Journal
Source(s): Cancers, Vol 13, Iss 3824, p 3824 (2021)
Abstract: Among new prognostic factors for breast cancer, the most promising one seems to be FGD3 (Facio-Genital Dysplasia 3) gene, whose expression improves outcome by inhibiting cell migration. The aim of the study was to evaluate the prognostic role of FGD3 i...