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Advanced Search Results For "Brennan, Katie"

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 "Brennan, Katie"
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Presentation, management, and outcomes of cauda equina syndrome up to one year after surgery, using clinician and participant reporting: A multi-centre prospective cohort studyResearch in context

Publication Type: Academic Journal

Source(s): The Lancet Regional Health. Europe, Vol 24, Iss , Pp 100545- (2023)

Abstract: Summary: Background: Cauda equina syndrome (CES) results from nerve root compression in the lumbosacral spine, usually due to a prolapsed intervertebral disc. Evidence for management of CES is limited by its infrequent occurrence and lack of standardis...

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Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study

Publication Type: Academic Journal

Source(s): The Lancet: Digital Health, Vol 4, Iss 4, Pp e220-e234 (2022)

Abstract: Summary: Background: Dexamethasone was the first intervention proven to reduce mortality in patients with COVID-19 being treated in hospital. We aimed to evaluate the adoption of corticosteroids in the treatment of COVID-19 in the UK after the RECOVERY...

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Fermentation Enhances the Anti-Inflammatory and Anti-Platelet Properties of Both Bovine Dairy and Plant-Derived Dairy Alternatives

Publication Type: Academic Journal

Source(s): Fermentation, Vol 8, Iss 292, p 292 (2022)

Abstract: Within the present study, the effects of fermentation on the anti-inflammatory and anti-platelet properties of both homemade and commercially purchased bovine dairy and almond, coconut, and rice-based dairy alternatives were evaluated. The extracted to...

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Behavioural interventions to promote physical activity in a multiethnic population at high risk of diabetes: PROPELS three-arm RCT

Publication Type: Academic Journal

Source(s): Health Technology Assessment, Vol 25, Iss 77 (2021)

Abstract: Background: Type 2 diabetes is a leading cause of mortality globally and accounts for significant health resource expenditure. Increased physical activity can reduce the risk of diabetes. However, the longer-term clinical effectiveness and cost-effecti...

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The impact of viral mutations on recognition by SARS-CoV-2 specific T cells

Publication Type: Academic Journal

Source(s): iScience, Vol 24, Iss 11, Pp 103353- (2021)

Abstract: Summary: We identify amino acid variants within dominant SARS-CoV-2 T cell epitopes by interrogating global sequence data. Several variants within nucleocapsid and ORF3a epitopes have arisen independently in multiple lineages and result in loss of reco...

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Determining the level of social distancing necessary to avoid future COVID-19 epidemic waves: a modelling study for North East London

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Abstract: Abstract Determining the level of social distancing, quantified here as the reduction in daily number of social contacts per person, i.e. the daily contact rate, needed to maintain control of the COVID-19 epidemic and not exceed acute bed capacity in c...

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Placebo comparator group selection and use in surgical trials: the ASPIRE project including expert workshop

Publication Type: Academic Journal

Source(s): Health Technology Assessment, Vol 25, Iss 53 (2021)

Abstract: Background: The use of placebo comparisons for randomised trials assessing the efficacy of surgical interventions is increasingly being considered. However, a placebo control is a complex type of comparison group in the surgical setting and, although p...

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The addition of sodium thiosulphate to hyperthermic intraperitoneal chemotherapy with cisplatin in ovarian cancer

Publication Type: Academic Journal

Source(s): Gynecologic Oncology Reports, Vol 37, Iss , Pp 100796- (2021)

Abstract: Cisplatin based hyperthermic intraperitoneal chemotherapy (HIPEC) has been shown to prolong recurrence free and overall survival of women with ovarian cancer who have responded to neoadjuvant chemotherapy. The aim of this study was to assess the impact...

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Surgical site infection after gastrointestinal surgery in children: an international, multicentre, prospective cohort study

Publication Type: Academic Journal

Source(s): BMJ Global Health, Vol 5, Iss 12 (2020)

Abstract: Introduction Surgical site infection (SSI) is one of the most common healthcare-associated infections (HAIs). However, there is a lack of data available about SSI in children worldwide, especially from low-income and middle-income countries. This study...

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