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Advanced Search Results For "Bruijn M"

1 - 10 of 3,904 results for
 "Bruijn M"
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CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)

Abstract: The origin of cancer-associated fibroblasts (CAFs) in cancer remains to be identified. Here, single-cell transcriptomics, in vivo and in vitro studies suggest that CD26+ and CD26- normal fibroblasts transform into distinct CAF subpopulations in mouse m...

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Flood risk management through a resilience lens

Publication Type: Academic Journal

Source(s): Communications Earth & Environment, Vol 3, Iss 1, Pp 1-4 (2022)

Abstract: To prevent floods from becoming disasters, social vulnerability must be integrated into flood risk management. This Comment advocates that the welfare of different societal groups should be included by adding recovery capacity, impacts of beyond-design...

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MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)

Abstract: Tripe-negative breast cancers poorly respond to immune checkpoint inhibition therapy, due to their immune-hostile tumour microenvironment. Authors here show that the oncogene MYC plays a pivotal role in suppressing anti-tumour immunity via directly reg...

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Coupling a large-scale hydrological model (CWatM v1.1) with a high-resolution groundwater flow model (MODFLOW 6) to assess the impact of irrigation at regional scale

Publication Type: Academic Journal

Source(s): Geoscientific Model Development, Vol 15, Pp 7099-7120 (2022)

Abstract: In the context of changing climate and increasing water demand, large-scale hydrological models are helpful for understanding and projecting future water resources across scales. Groundwater is a critical freshwater resource and strongly controls river...

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The energetic effect of hip flexion and retraction in walking at different speeds: a modeling study

Publication Type: Academic Journal

Source(s): PeerJ, Vol 11, p e14662 (2023)

Abstract: In human walking, power for propulsion is generated primarily via ankle and hip muscles. The addition of a ‘passive’ hip spring to simple bipedal models appears more efficient than using only push-off impulse, at least, when hip spring associated energ...

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Associations between primary motor cortex organization, motor control and sensory tests during the clinical course of low back pain. A protocol for a cross-sectional and longitudinal case-control study

Publication Type: Academic Journal

Source(s): Contemporary Clinical Trials Communications, Vol 30, Iss , Pp 101022- (2022)

Abstract: Background: In people with low back pain (LBP), altered motor control has been related to reorganization of the primary motor cortex (M1). Sensory impairments in LBP have also been suggested to be associated with reorganization of M1. Little is known a...

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Search for non-standard neutrino interactions with 10 years of ANTARES data

Publication Type: Academic Journal

Source(s): Journal of High Energy Physics, Vol 2022, Iss 7, Pp 1-22 (2022)

Abstract: Abstract Non-standard interactions of neutrinos arising in many theories beyond the Standard Model can significantly alter matter effects in atmospheric neutrino propagation through the Earth. In this paper, a search for deviations from the prediction ...

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Quantitative and qualitative changes in platelet traits of sunitinib-treated patients with renal cell carcinoma in relation to circulating sunitinib levels: a proof-of-concept study

Publication Type: Academic Journal

Source(s): BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)

Abstract: Abstract Background Tyrosine kinase inhibitors (TKIs), such as sunitinib, are used for cancer treatment, but may also affect platelet count and function with possible hemostatic consequences. Here, we investigated whether patient treatment with the TKI...

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Hydrological concept formation inside long short-term memory (LSTM) networks

Publication Type: Academic Journal

Source(s): Hydrology and Earth System Sciences, Vol 26, Pp 3079-3101 (2022)

Abstract: Neural networks have been shown to be extremely effective rainfall-runoff models, where the river discharge is predicted from meteorological inputs. However, the question remains: what have these models learned? Is it possible to extract information ab...

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