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Advanced Search Results For "Burgess, Matthew"

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 "Burgess, Matthew"
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Systematic Mendelian randomization using the human plasma proteome to discover potential therapeutic targets for stroke

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

Abstract: Mendelian randomization can be used to mimic the effects of protein-targeting drugs in a population of individuals. Here, the authors have identified potential causal proteins for stroke in a two-sample Mendelian randomization framework, providing pote...

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Economic evaluation of a Decision Support Tool to guide intensity of mental health care in general practice: the Link-me pragmatic randomised controlled trial

Publication Type: Academic Journal

Source(s): BMC Primary Care, Vol 23, Iss 1, Pp 1-10 (2022)

Abstract: Abstract Background This paper reports on the cost-effectiveness evaluation of Link-me – a digitally supported, systematic approach to triaging care for depression and anxiety in primary care that uses a patient-completed Decision Support Tool (DST). M...

Improving crop yield potential: Underlying biological processes and future prospects

Publication Type: Academic Journal

Source(s): Food and Energy Security, Vol 12, Iss 1, Pp n/a-n/a (2023)

Abstract: Abstract The growing world population and global increases in the standard of living both result in an increasing demand for food, feed and other plant‐derived products. In the coming years, plant‐based research will be among the major drivers ensuring...

A randomized pilot study of the prophylactic effect of ketamine on laboratory-induced stress in healthy adults

Publication Type: Academic Journal

Source(s): Neurobiology of Stress, Vol 22, Iss , Pp 100505- (2023)

Abstract: Background: Stress exposure is a key risk factor for the development of major depressive disorder and posttraumatic stress disorder. Enhancing stress resilience in at-risk populations could potentially protect against stress-induced disorders. The admi...

Vaccine-induced time- and age-dependent mucosal immunity to gastrointestinal parasite infection

Publication Type: Academic Journal

Source(s): npj Vaccines, Vol 7, Iss 1, Pp 1-9 (2022)

Abstract: Abstract Individuals vary broadly in their response to vaccination and subsequent challenge infection, with poor vaccine responders causing persistence of both infection and transmission in populations. Yet despite having substantial economic and socie...

Indices of complement activation and coagulation changes in trauma patients

Publication Type: Academic Journal

Source(s): Trauma Surgery & Acute Care Open, Vol 7, Iss 1 (2022)

Abstract: Objectives Early complementopathy and coagulopathy are shown often after trauma. However, the prevalence of any interplay between complement cascade (ComC) and coagulation cascade (CoaC) after trauma remains unclear. This study intended to explore whet...

Feasibility of measles and rubella vaccination programmes for disease elimination: a modelling study

Publication Type: Academic Journal

Source(s): The Lancet Global Health, Vol 10, Iss 10, Pp e1412-e1422 (2022)

Abstract: Summary: Background: Marked reductions in the incidence of measles and rubella have been observed since the widespread use of the measles and rubella vaccines. Although no global goal for measles eradication has been established, all six WHO regions ha...

Personalized digital intervention for depression based on social rhythm principles adds significantly to outpatient treatment

Publication Type: Academic Journal

Source(s): Frontiers in Digital Health, Vol 4 (2022)

Abstract: We conducted a 16-week randomized controlled trial in psychiatric outpatients with a lifetime diagnosis of a mood and/or anxiety disorder to measure the impact of a first-of-its-kind precision digital intervention software solution based on social rhyt...

Durability of Antibody Response and Frequency of SARS-CoV-2 Infection 6 Months after COVID-19 Vaccination in Healthcare Workers

Publication Type: Academic Journal

Source(s): Emerging Infectious Diseases, Vol 28, Iss 4, Pp 828-832 (2022)

Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies decay but persist 6 months postvaccination; lower levels of neutralizing titers persist against Delta than wild-type virus. Of 227 vaccinated healthcare workers tested, only 2 expe...

VOICE–Validating Outcomes by Including Consumer Experience: A Study Protocol to Develop a Patient Reported Experience Measure for Aboriginal and Torres Strait Islander Peoples Accessing Primary Health Care

Publication Type: Academic Journal

Source(s): International Journal of Environmental Research and Public Health, Vol 20, Iss 357, p 357 (2022)

Abstract: Aboriginal and Torres Strait Islander peoples’ (hereafter respectfully referred to as Indigenous Australians) experiences of health care are shaped by historical, social and cultural factors, with cultural security critical to effective care provision ...

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