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Advanced Search Results For "Campbell, Randall C."

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 "Campbell, Randall C."
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Regulation of purine metabolism connects KCTD13 to a metabolic disorder with autistic features

Publication Type: Academic Journal

Source(s): iScience, Vol 24, Iss 1, Pp 101935- (2021)

Abstract: Summary: Genetic variation of the 16p11.2 deletion locus containing the KCTD13 gene and of CUL3 is linked with autism. This genetic connection suggested that substrates of a CUL3-KCTD13 ubiquitin ligase may be involved in disease pathogenesis. Comparis...

Maize Genomes to Fields: 2014 and 2015 field season genotype, phenotype, environment, and inbred ear image datasets

Publication Type: Academic Journal

Source(s): BMC Research Notes, Vol 11, Iss 1, Pp 1-5 (2018)

Abstract: Abstract Objectives Crop improvement relies on analysis of phenotypic, genotypic, and environmental data. Given large, well-integrated, multi-year datasets, diverse queries can be made: Which lines perform best in hot, dry environments? Which alleles o...

Diagnosing mild traumatic brain injury using saliva RNA compared to cognitive and balance testing

Publication Type: Academic Journal

Source(s): Clinical and Translational Medicine, Vol 10, Iss 6, Pp n/a-n/a (2020)

Abstract: Abstract Background Early, accurate diagnosis of mild traumatic brain injury (mTBI) can improve clinical outcomes for patients, but mTBI remains difficult to diagnose because of reliance on subjective symptom reports. An objective biomarker could incre...

Effect of Bmi1 over-expression on gene expression in adult and embryonic murine neural stem cells

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)

Abstract: Abstract The ability of isolated neural stem cells (NSCs) to proliferate as neurospheres is indicative of their competence as stem cells, and depends critically on the polycomb group (PcG) member Bmi1: knockdown of Bmi1 results in defective proliferati...


The effect of artificial selection on phenotypic plasticity in maize

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)

Abstract: Breeding has increased crop productivity, but whether it has also changed phenotypic plasticity is unclear. Here, the authors find maize genomic regions selected for high productivity show reduced contribution to genotype by environment variation and p...


Taxonomy based on science is necessary for global conservation.

Publication Type: Academic Journal

Source(s): PLoS Biology, Vol 16, Iss 3, p e2005075 (2018)

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.

Publication Type: Academic Journal

Source(s): PLoS Genetics, Vol 9, Iss 6, p e1003500 (2013)

Abstract: Given the anthropometric differences between men and women and previous evidence of sex-difference in genetic effects, we conducted a genome-wide search for sexually dimorphic associations with height, weight, body mass index, waist circumference, hip ...


Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

Publication Type: Academic Journal

Source(s): PLoS Genetics, Vol 8, Iss 3, p e1002607 (2012)

Abstract: Circulating levels of adiponectin, a hormone produced predominantly by adipocytes, are highly heritable and are inversely associated with type 2 diabetes mellitus (T2D) and other metabolic traits. We conducted a meta-analysis of genome-wide association...


A genome-wide association search for type 2 diabetes genes in African Americans.

Publication Type: Academic Journal

Source(s): PLoS ONE, Vol 7, Iss 1, p e29202 (2012)

Abstract: African Americans are disproportionately affected by type 2 diabetes (T2DM) yet few studies have examined T2DM using genome-wide association approaches in this ethnicity. The aim of this study was to identify genes associated with T2DM in the African A...


Multiple cytokines are released when blood from patients with tuberculosis is stimulated with Mycobacterium tuberculosis antigens.

Publication Type: Academic Journal

Source(s): PLoS ONE, Vol 6, Iss 11, p e26545 (2011)

Abstract: BackgroundMycobacterium tuberculosis (Mtb) infection may cause overt disease or remain latent. Interferon gamma release assays (IGRAs) detect Mtb infection, both latent infection and infection manifesting as overt disease, by measuring whole-blood inte...