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Advanced Search Results For "Carraro, Valentina"

1 - 10 of 269 results for
 "Carraro, Valentina"
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Decoding mechanism of action and sensitivity to drug candidates from integrated transcriptome and chromatin state

Publication Type:Academic Journal

Source(s):eLife, Vol 11 (2022)

Abstract:Omics-based technologies are driving major advances in precision medicine, but efforts are still required to consolidate their use in drug discovery. In this work, we exemplify the use of multi-omics to support the development of 3-chloropiperidines, a...

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Phosphoproteomic Analysis Reveals a Different Proteomic Profile in Pediatric Patients With T-Cell Lymphoblastic Lymphoma or T-Cell Acute Lymphoblastic Leukemia

Publication Type:Academic Journal

Source(s):Frontiers in Oncology, Vol 12 (2022)

Abstract:T-cell lymphoblastic lymphoma (T-LBL) and lymphoblastic leukemia (T-ALL) arise from the transformation of precursor T-cells sharing common morphological and immunophenotypic features. Despite this, T-LBL and T-ALL show different genomic/transcriptomic ...

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Impact of COVID-19 in Children with Chronic Lung Diseases

Publication Type:Academic Journal

Source(s):International Journal of Environmental Research and Public Health, Vol 19, Iss 11483, p 11483 (2022)

Abstract:Background: since December 2019, the world has become victim of the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The aim of our narrative review is to analyze the impact of COVID-1...

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Early Oral Nutritional Supplements in the Prevention of Wheezing, Asthma, and Respiratory Infections

Publication Type:Academic Journal

Source(s):Frontiers in Pediatrics, Vol 10 (2022)

Abstract:Wheezing, asthma, and respiratory infections (RTI) are among the most common causes of morbidity in children and their economic and social burden could be significantly reduced by specific prevention strategies. Epidemiological studies suggest that low...

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Assessment of Respiratory Function and Need for Noninvasive Ventilation in a Cohort of Patients with Myotonic Dystrophy Type 1 Followed at One Single Expert Center

Publication Type:Academic Journal

Source(s):Canadian Respiratory Journal, Vol 2022 (2022)

Abstract:Introduction. Respiratory insufficiency is one of the main causes of death in myotonic dystrophy type 1 (DM1). Although there is general consensus that these patients have a restrictive ventilatory pattern, hypoventilation, chronic hypercapnia, and sle...

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Preliminary Evidence on Pulmonary Function after Asymptomatic and Mild COVID-19 in Children

Publication Type:Academic Journal

Source(s):Children, Vol 9, Iss 952, p 952 (2022)

Abstract:Background: While it has been described that adults can develop long-lasting deterioration in pulmonary function (PF) after coronavirus disease 19 (COVID-19), regardless of disease severity, data on the long-term pneumological impact of SARS-CoV-2 infe...

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Pediatric asthma control during the COVID‐19 pandemic

Publication Type:Academic Journal

Source(s):Immunity, Inflammation and Disease, Vol 9, Iss 2, Pp 561-568 (2021)

Abstract:Abstract Background The lockdown imposed by the COVID‐19 pandemic resulted in a completely different style of life with possible effects on the attitude toward their disease in patients with chronic lung disease, such as asthma. The aim of our study wa...

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Psychosocial impact of Covid-19 outbreak on Italian asthmatic children and their mothers in a post lockdown scenario

Publication Type:Academic Journal

Source(s):Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)

Abstract:Abstract Italy was the first European country to fight the Covid-19 outbreak. To limit the transmission of the virus, the Italian Government imposed strict domestic quarantine policies and temporary closure of non-essential businesses and schools from ...

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TERT Promoter Mutations and rs2853669 Polymorphism: Useful Markers for Clinical Outcome Stratification of Patients With Oral Cavity Squamous Cell Carcinoma

Publication Type:Academic Journal

Source(s):Frontiers in Oncology, Vol 11 (2021)

Abstract:ObjectiveTo date, no useful prognostic biomarker exists for patients with oral squamous cell carcinoma (OCSCC), a tumour with uncertain biological behaviour and subsequent unpredictable clinical course. We aim to investigate the prognostic significance...

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Effects of Tolvaptan on Oxidative Stress in ADPKD: A Molecular Biological Approach

Publication Type:Academic Journal

Source(s):Journal of Clinical Medicine, Vol 11, Iss 402, p 402 (2022)

Abstract:Autosomal dominant polycystic disease (ADPKD) is the most frequent monogenic kidney disease. It causes progressive renal failure, endothelial dysfunction, and hypertension, all of which are strictly linked to oxidative stress (OxSt). Treatment with tol...

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