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P686: REAL-WORLD EFFICACY PROFILE OF ASCIMINIB IN AN ITALIAN, MULTI-RESISTANT CHRONIC-PHASE CHRONIC MYELOID LEUKEMIA (CP-CML) PATIENT POPULATION
Publication Type: Academic Journal
Source(s): HemaSphere, Vol 7, p e55133e1 (2023)
Conservative approach in lobar and segmental congenital emphysema: Lung function and clinical outcome
Publication Type: Academic Journal
Source(s): Journal of Pediatric Surgery Open, Vol 1, Iss , Pp 100008- (2023)
Abstract: Aim of the study: To evaluate clinical outcome and respiratory function in patients with congenital lobar/segmental emphysema (CLE/CSE) treated conservatively. Methods: In this single-centre retrospective study we included patients ≥5-year-old with a d...
Of fixes and glitches: Mixing metaphors for platform urbanism
Publication Type: Academic Journal
Source(s): Digital Geography and Society, Vol 4, Iss , Pp 100056- (2023)
Abstract: The growing influence of digital platforms on cities has captured the attention of urban scholars, marking a ‘platform pivot’ in digital geography and urban research. This article reviews emerging literature on platform urbanism, using the metaphors of...
Lung Function in Children with Primary Ciliary Dyskinesia
Publication Type: Academic Journal
Source(s): Children, Vol 10, Iss 290, p 290 (2023)
Abstract: Background: Primary ciliary dyskinesia (PCD) is characterized by impaired mucociliary clearance that results in accumulation of mucus and bacteria in the airways. Lower respiratory tract infections lead to airway remodeling and lung function impairment...
Decoding mechanism of action and sensitivity to drug candidates from integrated transcriptome and chromatin state
Publication Type: Academic Journal
Source(s): eLife, Vol 11 (2022)
Abstract: Omics-based technologies are driving major advances in precision medicine, but efforts are still required to consolidate their use in drug discovery. In this work, we exemplify the use of multi-omics to support the development of 3-chloropiperidines, a...
Phosphoproteomic Analysis Reveals a Different Proteomic Profile in Pediatric Patients With T-Cell Lymphoblastic Lymphoma or T-Cell Acute Lymphoblastic Leukemia
Publication Type: Academic Journal
Source(s): Frontiers in Oncology, Vol 12 (2022)
Abstract: T-cell lymphoblastic lymphoma (T-LBL) and lymphoblastic leukemia (T-ALL) arise from the transformation of precursor T-cells sharing common morphological and immunophenotypic features. Despite this, T-LBL and T-ALL show different genomic/transcriptomic ...
The Effect of Green Tea as an Adjuvant to Enzyme Replacement Therapy on Oxidative Stress in Fabry Disease: A Pilot Study
Publication Type: Academic Journal
Source(s): Frontiers in Nutrition, Vol 9 (2022)
Abstract: Enzymatic replacement therapy (ERT) is not very effective in halting the progression of Fabry disease (FD) toward cardiovascular (CV)-renal remodeling, particularly in case of late diagnosis. FD patients have increased oxidative stress (OS), critical f...
Spending Time with Mothers as a Resource for Children with Chronic Diseases: A Comparison of Asthma, Type 1 Diabetes, and Cancer during COVID-19 Pandemic
Publication Type: Academic Journal
Source(s): International Journal of Environmental Research and Public Health, Vol 19, Iss 14126, p 14126 (2022)
Abstract: Due to the COVID-19 pandemic, many families had to manage new difficulties, especially those of chronically ill children. More and more research has focused on the negative effects of the pandemic on psychological wellbeing, while less is known about t...
Pediatric asthma control during the COVID‐19 pandemic
Publication Type: Academic Journal
Source(s): Immunity, Inflammation and Disease, Vol 9, Iss 2, Pp 561-568 (2021)
Abstract: Abstract Background The lockdown imposed by the COVID‐19 pandemic resulted in a completely different style of life with possible effects on the attitude toward their disease in patients with chronic lung disease, such as asthma. The aim of our study wa...
Psychosocial impact of Covid-19 outbreak on Italian asthmatic children and their mothers in a post lockdown scenario
Publication Type: Academic Journal
Source(s): Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract: Abstract Italy was the first European country to fight the Covid-19 outbreak. To limit the transmission of the virus, the Italian Government imposed strict domestic quarantine policies and temporary closure of non-essential businesses and schools from ...