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Advanced Search Results For "Clancy P"

1 - 10 of 19,374 results for
 "Clancy P"
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Efficient in planta production of amidated antimicrobial peptides that are active against drug-resistant ESKAPE pathogens

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)

Abstract: Antimicrobial peptides (AMPs) are next-generation antibiotics that can be used to combat drugresistant pathogens. Here, the authors report efficient production of bioactive amidated AMPs by transient expression in Nicotiana benthamiana line expressing ...


The patient clinical journey and socioeconomic impact of osteogenesis imperfecta: a systematic scoping review

Publication Type: Academic Journal

Source(s): Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-26 (2023)

Abstract: Abstract Background Osteogenesis imperfecta (OI) is a rare heritable connective tissue disorder primarily characterised by skeletal deformity and fragility, and an array of secondary features. The purpose of this review was to capture and quantify the ...

Transcriptomics secondary analysis of severe human infection with SARS-CoV-2 identifies gene expression changes and predicts three transcriptional biomarkers in leukocytes

Publication Type: Academic Journal

Source(s): Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1403-1413 (2023)

Abstract: SARS-CoV-2 is the causative agent of COVID-19, which has greatly affected human health since it first emerged. Defining the human factors and biomarkers that differentiate severe SARS-CoV-2 infection from mild infection has become of increasing interes...

Fluorescence and phosphorescence lifetime imaging reveals a significant cell nuclear viscosity and refractive index changes upon DNA damage

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)

Abstract: Abstract Cytoplasmic viscosity is a crucial parameter in determining rates of diffusion-limited reactions. Changes in viscosity are associated with several diseases, whilst nuclear viscosity determines gene integrity, regulation and expression. Yet how...


Health-related quality of life in inflammatory bowel disease: a comparison of patients receiving nurse-led versus conventional follow-up care

Publication Type: Academic Journal

Source(s): BMC Health Services Research, Vol 22, Iss 1, Pp 1-8 (2022)

Abstract: Abstract Background Inflammatory bowel disease (IBD), consisting of Crohn's disease (CD) and ulcerative colitis (UC), is a chronic disorder with a considerable negative impact on health-related quality of life (HRQoL). During the past decade, IBD nurse...

Hydrogel-based microfluidic device with multiplexed 3D in vitro cell culture

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Abstract: Abstract Microfluidic devices that combine an extracellular matrix environment, cells, and physiologically relevant perfusion, are advantageous as cell culture platforms. We developed a hydrogel-based, microfluidic cell culture platform by loading poly...


Blood donor biobank and HLA imputation as a resource for HLA homozygous cells for therapeutic and research use

Publication Type: Academic Journal

Source(s): Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-11 (2022)

Abstract: Abstract Background Allogeneic therapeutic cells may be rejected if they express HLA alleles not found in the recipient. As finding cell donors with a full HLA match to a recipient requires vast donor pools, the use of HLA homozygous cells has been sug...

Rapid protection of nonhuman primates against Marburg virus disease using a single low-dose VSV-based vaccineResearch in context

Publication Type: Academic Journal

Source(s): EBioMedicine, Vol 89, Iss , Pp 104463- (2023)

Abstract: Summary: Background: Marburg virus (MARV) is the causative agent of Marburg virus disease (MVD) which has a case fatality rate up to ∼90% in humans. Recently, there were cases reported in Guinea and Ghana highlighting this virus as a high-consequence p...

A quantitative analysis of factors which influence supplement use and doping among adolescent athletes in New Zealand

Publication Type: Academic Journal

Source(s): Frontiers in Sports and Active Living, Vol 5 (2023)

Abstract: ObjectivesDoping is a maladaptive behaviour which poses numerous risks and potentially enhances athletic performance while supplement use poses threats of positive, yet inadvertent, doping control results. Investigation is required to understand factor...

Stiffness tailoring in sinusoidal lattice structures through passive topology morphing using contact connections

Publication Type: Academic Journal

Source(s): Materials & Design, Vol 226, Iss , Pp 111649- (2023)

Abstract: Structures with adaptive stiffness characteristics present an opportunity to meet competing design requirements, thus achieving greater efficiency by the reconfiguration of their topology. Here, the potential of using changes in the topology of planar ...