Advanced Search Results For "Clancy P"

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Publication Type: Academic Journal

Source(s): Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)

Abstract: Antimicrobial peptides (AMPs) are next-generation antibiotics that can be used to combat drugresistant pathogens. Here, the authors report efficient production of bioactive amidated AMPs by transient expression in Nicotiana benthamiana line expressing ...

Publication Type: Academic Journal

Source(s): Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-26 (2023)

Abstract: Abstract Background Osteogenesis imperfecta (OI) is a rare heritable connective tissue disorder primarily characterised by skeletal deformity and fragility, and an array of secondary features. The purpose of this review was to capture and quantify the ...

Publication Type: Academic Journal

Source(s): Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1403-1413 (2023)

Abstract: SARS-CoV-2 is the causative agent of COVID-19, which has greatly affected human health since it first emerged. Defining the human factors and biomarkers that differentiate severe SARS-CoV-2 infection from mild infection has become of increasing interes...

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)

Abstract: Abstract Cytoplasmic viscosity is a crucial parameter in determining rates of diffusion-limited reactions. Changes in viscosity are associated with several diseases, whilst nuclear viscosity determines gene integrity, regulation and expression. Yet how...

Publication Type: Academic Journal

Source(s): BMC Health Services Research, Vol 22, Iss 1, Pp 1-8 (2022)

Abstract: Abstract Background Inflammatory bowel disease (IBD), consisting of Crohn's disease (CD) and ulcerative colitis (UC), is a chronic disorder with a considerable negative impact on health-related quality of life (HRQoL). During the past decade, IBD nurse...

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Abstract: Abstract Microfluidic devices that combine an extracellular matrix environment, cells, and physiologically relevant perfusion, are advantageous as cell culture platforms. We developed a hydrogel-based, microfluidic cell culture platform by loading poly...

Publication Type: Academic Journal

Source(s): Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-11 (2022)

Abstract: Abstract Background Allogeneic therapeutic cells may be rejected if they express HLA alleles not found in the recipient. As finding cell donors with a full HLA match to a recipient requires vast donor pools, the use of HLA homozygous cells has been sug...

Publication Type: Academic Journal

Source(s): EBioMedicine, Vol 89, Iss , Pp 104463- (2023)

Abstract: Summary: Background: Marburg virus (MARV) is the causative agent of Marburg virus disease (MVD) which has a case fatality rate up to ∼90% in humans. Recently, there were cases reported in Guinea and Ghana highlighting this virus as a high-consequence p...

Publication Type: Academic Journal

Source(s): Frontiers in Sports and Active Living, Vol 5 (2023)

Abstract: ObjectivesDoping is a maladaptive behaviour which poses numerous risks and potentially enhances athletic performance while supplement use poses threats of positive, yet inadvertent, doping control results. Investigation is required to understand factor...

Publication Type: Academic Journal

Source(s): Materials & Design, Vol 226, Iss , Pp 111649- (2023)

Abstract: Structures with adaptive stiffness characteristics present an opportunity to meet competing design requirements, thus achieving greater efficiency by the reconfiguration of their topology. Here, the potential of using changes in the topology of planar ...