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Indigenous Māori perspectives of smokefree parks
Publication Type: Academic Journal
Source(s): Australian and New Zealand Journal of Public Health, Vol 46, Iss 4, Pp 469-476 (2022)
Abstract: Abstract Objective: This study aims to understand the context of place associated with smoking in urban Hamilton parks from a Te Ao Māori perspective (the worldview of Māori, the Indigenous people of Aotearoa New Zealand). Methods: Our study approached...
Weakening and warming of the European Slope Current since the late 1990s attributed to basin-scale density changes
Publication Type: Academic Journal
Source(s): Ocean Science, Vol 18, Pp 549-564 (2022)
Abstract: Oceanic influences on shelf seas are mediated by flow along and across continental slopes, with consequences for regional hydrography and ecosystems. Here we present evidence for the variable North Atlantic influence on European shelf seas over the las...
Paediatric COVID-19 mortality: a database analysis of the impact of health resource disparity
Publication Type: Academic Journal
Source(s): BMJ Paediatrics Open, Vol 6, Iss 1 (2022)
Abstract: Background The impact of the COVID-19 pandemic on paediatric populations varied between high-income countries (HICs) versus low-income to middle-income countries (LMICs). We sought to investigate differences in paediatric clinical outcomes and identify...
Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study
Publication Type: Academic Journal
Source(s): The Lancet: Digital Health, Vol 4, Iss 4, Pp e220-e234 (2022)
Abstract: Summary: Background: Dexamethasone was the first intervention proven to reduce mortality in patients with COVID-19 being treated in hospital. We aimed to evaluate the adoption of corticosteroids in the treatment of COVID-19 in the UK after the RECOVERY...
Mass Cytometry Discovers Two Discrete Subsets of CD39−Treg Which Discriminate MGUS From Multiple Myeloma
Publication Type: Academic Journal
Source(s): Frontiers in Immunology, Vol 10 (2019)
Abstract: Multiple Myeloma (MM) is preceded by the clinically stable condition monoclonal gammopathy of undetermined significance (MGUS). Critical immune events that discriminate MGUS from newly diagnosed MM (ND)MM patients remain unknown, but may involve change...
Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity.
Publication Type: Academic Journal
Source(s): PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0007159 (2019)
Abstract: There is a significant need for improved treatments for onchocerciasis and lymphatic filariasis, diseases caused by filarial worm infection. In particular, an agent able to selectively kill adult worms (macrofilaricide) would be expected to substantial...
Comparison of Hepatic Arterial Infusion Pump Chemotherapy vs Resection for Patients With Multifocal Intrahepatic Cholangiocarcinoma
Publication Type: Periodical
Source(s): JAMA Surgery; July 2022, Vol. 157 Issue: 7 p590-596, 7p
Abstract: IMPORTANCE: Intrahepatic cholangiocarcinoma (iCCA) is often multifocal (ie, satellites or intrahepatic metastases) at presentation. OBJECTIVE: To compare the overall survival (OS) of patients with multifocal iCCA after hepatic arterial infusion pump (H...
Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study
Publication Type: Periodical
Source(s): The Lancet Digital Health; April 2022, Vol. 4 Issue: 4 pe220-e234, 15p
Abstract: Dexamethasone was the first intervention proven to reduce mortality in patients with COVID-19 being treated in hospital. We aimed to evaluate the adoption of corticosteroids in the treatment of COVID-19 in the UK after the RECOVERY trial publication on...
Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
Publication Type: Periodical
Source(s): The Lancet; February 2022, Vol. 399 Issue: 10325 p665-676, 12p
Abstract: Casirivimab and imdevimab are non-competing monoclonal antibodies that bind to two different sites on the receptor binding domain of the SARS-CoV-2 spike glycoprotein, blocking viral entry into host cells. We aimed to evaluate the efficacy and safety o...
Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
Publication Type: Periodical
Source(s): The Lancet; January 2022, Vol. 399 Issue: 10320 p143-151, 9p
Abstract: Aspirin has been proposed as a treatment for COVID-19 on the basis of its anti-thrombotic properties. We aimed to evaluate the efficacy and safety of aspirin in patients admitted to hospital with COVID-19.