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A suite of PCR-LwCas13a assays for detection and genotyping of Treponema pallidum in clinical samples
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Abstract: Clinical diagnosis of Treponema pallidum subspecies pallidum (TPA), the causative agent of syphilis, depends upon serological testing, which has reduced sensitivity for some stages of the disease. Accompanying methods to complement serological testing ...
Ethnoracial Disparities in SARS-CoV-2 Seroprevalence in a Large Cohort of Individuals in Central North Carolina from April to December 2020
Publication Type: Academic Journal
Source(s): mSphere, Vol 7, Iss 3 (2022)
Abstract: ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of deaths around the world within the past 2 years. Transmission within the United States has been heterogeneously distributed by geography and social factors wit...
Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness
Publication Type: Academic Journal
Source(s): eLife, Vol 10 (2021)
Abstract: The emergence of mutant K13-mediated artemisinin (ART) resistance in Plasmodium falciparum malaria parasites has led to widespread treatment failures across Southeast Asia. In Africa, K13-propeller genotyping confirms the emergence of the R561H mutatio...
A novel CRISPR-based malaria diagnostic capable of Plasmodium detection, species differentiation, and drug-resistance genotyping
Publication Type: Academic Journal
Source(s): EBioMedicine, Vol 68, Iss , Pp 103415- (2021)
Abstract: Background: CRISPR-based diagnostics are a new class of highly sensitive and specific assays with multiple applications in infectious disease diagnosis. SHERLOCK, or Specific High-Sensitivity Enzymatic Reporter UnLOCKing, is one such CRISPR-based diagn...
Real-World Visual And Clinical Outcomes For Patients With Neovascular Age-Related Macular Degeneration Treated With Intravitreal Ranibizumab: An 8-Year Observational Cohort (AMD8)
Publication Type: Academic Journal
Source(s): Clinical Ophthalmology, Vol Volume 13, Pp 2461-2467 (2019)
Abstract: Faye Horner, Peck-Lin Lip, Hannah Clark, Randhir Chavan, Ambreen Sarmad, Bushra Mushtaq Birmingham and Midland Eye Centre, Birmingham, UKCorrespondence: Bushra MushtaqBirmingham and Midland Eye Centre, City Hospital, Dudley Road, Birmingham B18 7QH, UK...
The Obligate Intracellular Bacterial Pathogen Anaplasma phagocytophilum Exploits Host Cell Multivesicular Body Biogenesis for Proliferation and Dissemination
Publication Type: Academic Journal
Source(s): mBio, Vol 13, Iss 6 (2022)
Abstract: ABSTRACT Anaplasma phagocytophilum is the etiologic agent of the emerging infection, granulocytic anaplasmosis. This obligate intracellular bacterium lives in a host cell-derived vacuole that receives membrane traffic from multiple organelles to fuel i...
An interprofessional clinic for adults with Turner syndrome: the patient perspective.
Publication Type: Academic Journal
Source(s): Climacteric; Dec2022, Vol. 25 Issue 6, p609-614, 6p
Abstract: Copyright of Climacteric is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or em...
Eye Movement Abnormalities in Glaucoma Patients: A Review.
Publication Type: Academic Journal
Source(s): Eye & Brain; Sep2022, Vol. 14, p83-114, 32p
Abstract: Copyright of Eye & Brain is the property of Dove Medical Press Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or ...
Judiciary Act is Passed.
Publication Type: Reference
Source(s): Salem Press Encyclopedia, 2021. 3p.
- Clark, John G.; O’Brien, Charles H.
Abstract: The Constitution of the United States created the basic framework for a national government. It remained for the First Congress, meeting in New York in April, 1789, to implement the document. Few congresses have been of greater importance than the firs...
Cytomegalovirus (CMV).
Publication Type: Reference
Source(s): Magill’s Medical Guide (Online Edition), 2022. 2p.
- Clark, Nancy Handshaw, Ph.D.; Hawley, H. Bradford, M.D.
Abstract: Cytomegalovirus (CMV) is a member of the herpes virus group that includes such viruses as the Epstein-Barr virus, which causes infectious mononucleosis, and the varicella-zoster virus, which causes chickenpox. CMV is a ubiquitous virus that is transmit...