scroll to top
0

Mobile Menu

Header Layout

EBSCO Auth Banner

Let's find your institution. Click here.

Page title

Advanced Search Results For "Conzelmann, Thomas"

1 - 10 of 147 results for
 "Conzelmann, Thomas"
Results per page:

Anticholinergic Drug Exposure Increases the Risk of Delirium in Older Patients Undergoing Elective Surgery

Publication Type:Academic Journal

Source(s):Frontiers in Medicine, Vol 9 (2022)

Abstract:IntroductionPostoperative delirium (POD) is a common and serious adverse event of surgery in older people. Because of its great impact on patients' safety and quality of life, identification of modifiable risk factors could be useful. Although preopera...

View details

Inhibitors of Activin Receptor-like Kinase 5 Interfere with SARS-CoV-2 S-Protein Processing and Spike-Mediated Cell Fusion via Attenuation of Furin Expression

Publication Type:Academic Journal

Source(s):Viruses, Vol 14, Iss 1308, p 1308 (2022)

Abstract:Screening of a protein kinase inhibitor library identified SB431542, targeting activin receptor-like kinase 5 (ALK5), as a compound interfering with SARS-CoV-2 replication. Since ALK5 is implicated in transforming growth factor β (TGF-β) signaling and ...

View details

Drug Inhibition of SARS-CoV-2 Replication in Human Pluripotent Stem Cell–Derived Intestinal OrganoidsSummary

Publication Type:Academic Journal

Source(s):Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 935-948 (2021)

Abstract:Background and aims: The COVID-19 pandemic has spread worldwide and poses a severe health risk. While most patients present mild symptoms, descending pneumonia can lead to severe respiratory insufficiency. Up to 50% of patients show gastrointestinal sy...

View details

Presurgical Screening Improves Risk Prediction for Delirium in Elective Surgery of Older Patients: The PAWEL RISK Study

Publication Type:Academic Journal

Source(s):Frontiers in Aging Neuroscience, Vol 13 (2021)

Abstract:Introduction: The number of elective surgeries for patients who are over 70 years of age is continuously growing. At the same time, postoperative delirium (POD) is common in older patients (5–60%) depending on predisposing risk factors, such as multimo...

View details

The genetic architecture of human brainstem structures and their involvement in common brain disorders

Publication Type:Academic Journal

Source(s):Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)

Abstract:The genetic architecture underlying brainstem regions and how this links to common brain disorders is not well understood. Here, the authors use MRI and GWAS data from 27,034 individuals to identify genetic and morphological brainstem features that inf...

View details

A whole-brain connectivity map of mouse insular cortex

Publication Type:Academic Journal

Source(s):eLife, Vol 9 (2020)

Abstract:The insular cortex (IC) plays key roles in emotional and regulatory brain functions and is affected across psychiatric diseases. However, the brain-wide connections of the mouse IC have not been comprehensively mapped. Here, we traced the whole-brain i...

View details

Patient safety, cost-effectiveness, and quality of life: reduction of delirium risk and postoperative cognitive dysfunction after elective procedures in older adults—study protocol for a stepped-wedge cluster randomized trial (PAWEL Study)

Publication Type:Academic Journal

Source(s):Trials, Vol 20, Iss 1, Pp 1-15 (2019)

Abstract:Abstract Background Postoperative delirium is a common disorder in older adults that is associated with higher morbidity and mortality, prolonged cognitive impairment, development of dementia, higher institutionalization rates, and rising healthcare co...

View details

Myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model

Publication Type:Academic Journal

Source(s):Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)

Abstract:Oligodendrocyte damage is a key component of demyelinating diseases. Here, the authors use in vivolight and correlated electron microscopy in EAE mouse models, and find early damage occurs at the myelin sheath before spreading to the oligodendrocyte ce...

View details

Immunogenicity Studies in Carnivores Using a Rabies Virus Construct with a Site-Directed Deletion in the Phosphoprotein

Publication Type:Academic Journal

Source(s):Advances in Preventive Medicine, Vol 2011 (2011)

Abstract:Different approaches have been applied to develop highly attenuated rabies virus vaccines for oral vaccination of mesocarnivores. One prototype vaccine construct is SAD dIND1, which contains a deletion in the P-gene severely limiting the inhibition of ...

View details

banner_970x250 (970x250)

sponsored