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Advanced Search Results For "Cook, Rebecca A."

1 - 10 of 1,938 results for
 "Cook, Rebecca A."
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Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)

Abstract: The QT interval is a heritable electrocardiographic measure associated with arrhythmia risk when prolonged. Here, the authors used a series of genetic analyses to identify genetic loci, pathways, therapeutic targets, and relationships with cardiovascul...

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Combined Dusp4 and p53 loss with Dbf4 amplification drives tumorigenesis via cell cycle restriction and replication stress escape in breast cancer

Publication Type: Academic Journal

Source(s): Breast Cancer Research, Vol 24, Iss 1, Pp 1-16 (2022)

Abstract: Abstract Aim Deregulated signaling pathways are a hallmark feature of oncogenesis and driver of tumor progression. Dual specificity protein phosphatase 4 (DUSP4) is a critical negative regulator of the mitogen-activated protein kinase (MAPK) pathway an...

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SARS-CoV-2 Delta–Omicron Recombinant Viruses, United States

Publication Type: Academic Journal

Source(s): Emerging Infectious Diseases, Vol 28, Iss 7, Pp 1442-1445 (2022)

Abstract: To detect new and changing SARS-CoV-2 variants, we investigated candidate Delta–Omicron recombinant genomes from Centers for Disease Control and Prevention national genomic surveillance. Laboratory and bioinformatic investigations identified and valida...

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Sustainable management of groundwater extraction: An Australian perspective on current challenges

Publication Type: Academic Journal

Source(s): Journal of Hydrology: Regional Studies, Vol 44, Iss , Pp 101262- (2022)

Abstract: Study region: Australia Study focus: Our incomplete knowledge of groundwater systems and processes imposes barriers in attempting to manage groundwater sustainably. Challenges also arise through complex institutional arrangements and decision-making pr...

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Academic and Community ICUs Participating in a Critical Care Randomized Trial: A Comparison of Patient Characteristics and Trial Metrics

Publication Type: Academic Journal

Source(s): Critical Care Explorations, Vol 4, Iss 11, p e0794 (2022)

Abstract: OBJECTIVES:. Clinical research in Canada is conducted primarily in “academic” hospitals, whereas most clinical care is provided in “community” hospitals. The objective of this nested observational study was to compare patient characteristics, outcomes,...

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COVID-19 and mental health: A systematic review of international medical student surveys

Publication Type: Academic Journal

Source(s): Frontiers in Psychology, Vol 13 (2022)

Abstract: BackgroundThe medical school curriculum has imposed psychological stressors on students worldwide, some of which may induce feelings of increased depression and anxiety. Meanwhile, the COVID-19 pandemic has exacerbated the feelings of stress, depressio...

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Using machine learning to predict help-seeking among 2016–2018 Pregnancy Risk Assessment Monitoring System participants with postpartum depression symptoms

Publication Type: Academic Journal

Source(s): Women's Health, Vol 18 (2022)

Abstract: Background: Despite the importance of early identification and treatment, postpartum depression often remains largely undiagnosed with unreported symptoms. While research has identified several factors as prompting help-seeking for postpartum depressio...

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An Updated Perspective on the Dual-Track Model of Enterocyte Fat Metabolism

Publication Type: Academic Journal

Source(s): Journal of Lipid Research, Vol 63, Iss 11, Pp 100278- (2022)

Abstract: The small intestinal epithelium has classically been envisioned as a conduit for nutrient absorption, but appreciation is growing for a larger and more dynamic role for enterocytes in lipid metabolism. Considerable gaps remain in our knowledge of this ...

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Effects of Photon Radiation on DNA Damage, Cell Proliferation, Cell Survival, and Apoptosis of Murine and Human Mesothelioma Cell Lines

Publication Type: Academic Journal

Source(s): Advances in Radiation Oncology, Vol 7, Iss 6, Pp 101013- (2022)

Abstract: Purpose: To characterize the cellular responses of murine and human mesothelioma cell lines to different doses of photon radiation with a long-term aim of optimizing a clinically relevant in vivo model in which to study the interaction of radiation the...

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Evaluating implementation of Diabetes Self-Management Education in Maryland County, Liberia: protocol for a pilot prospective cohort study

Publication Type: Academic Journal

Source(s): BMJ Open, Vol 12, Iss 10 (2022)

Abstract: Introduction Achieving glycaemic targets for people living with diabetes (PLWD) is challenging, especially in settings with limited resources. Programmes need to address gaps in knowledge, skills and self-management. Diabetes Self-Management Education ...

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