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3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract: Abstract Ependymoma is a tumor of the brain or spinal cord. The two most common and aggressive molecular groups of ependymoma are the supratentorial ZFTA-fusion associated and the posterior fossa ependymoma group A. In both groups, tumors occur mainly ...
Neurophysiological measures of auditory sensory processing are associated with adaptive behavior in children with Autism Spectrum Disorder
Publication Type: Academic Journal
Source(s): Journal of Neurodevelopmental Disorders, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract: Abstract Background Atypical auditory cortical processing is consistently found in scalp electrophysiological and magnetoencephalographic studies of Autism Spectrum Disorder (ASD), and may provide a marker of neuropathological brain development. Howeve...
Adeno-Associated Virus 2 and Human Adenovirus F41 in Wastewater during Outbreak of Severe Acute Hepatitis in Children, Ireland
Publication Type: Academic Journal
Source(s): Emerging Infectious Diseases, Vol 29, Iss 4, Pp 751-760 (2023)
Abstract: During April–July 2022, outbreaks of severe acute hepatitis of unknown etiology (SAHUE) were reported in 35 countries. Five percent of cases required liver transplantation, and 22 patients died. Viral metagenomic studies of clinical samples from SAHUE ...
Investigating the effectiveness of three school based interventions for preventing psychotic experiences over a year period – a secondary data analysis study of a randomized control trial
Publication Type: Academic Journal
Source(s): BMC Public Health, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract: Abstract Introduction Psychotic experiences (PEs) are associated with increased risk of later mental disorders and so could be valuable in prevention studies. However, to date few intervention studies have examined PEs. Given this lack of evidence, in ...
Dysregulated early transcriptional signatures linked to mast cell and interferon responses are implicated in COVID-19 severity
Publication Type: Academic Journal
Source(s): Frontiers in Immunology, Vol 14 (2023)
Abstract: BackgroundDysregulated immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are thought to underlie the progression of coronavirus disease 2019 (COVID-19) to severe disease. We sought to determine whether early hos...
Microbiome ethics, guiding principles for microbiome research, use and knowledge management
Publication Type: Academic Journal
Source(s): Environmental Microbiome, Vol 17, Iss 1, Pp 1-8 (2022)
Abstract: Abstract The overarching biological impact of microbiomes on their hosts, and more generally their environment, reflects the co-evolution of a mutualistic symbiosis, generating fitness for both. Knowledge of microbiomes, their systemic role, interactio...
Correction to: Investigating the effectiveness of three school based interventions for preventing psychotic experiences over a year period – a secondary data analysis study of a randomized control trial
Publication Type: Academic Journal
Source(s): BMC Public Health, Vol 23, Iss 1, Pp 1-1 (2023)
Dietary-Induced Bacterial Metabolites Reduce Inflammation and Inflammation-Associated Cancer via Vitamin D Pathway
Publication Type: Academic Journal
Source(s): International Journal of Molecular Sciences, Vol 24, Iss 1864, p 1864 (2023)
Abstract: Environmental factors, including westernised diets and alterations to the gut microbiota, are considered risk factors for inflammatory bowel diseases (IBD). The mechanisms underpinning diet-microbiota-host interactions are poorly understood in IBD. We ...
Microbiome Research as an Effective Driver of Success Stories in Agrifood Systems – A Selection of Case Studies
Publication Type: Academic Journal
Source(s): Frontiers in Microbiology, Vol 13 (2022)
Abstract: Increasing knowledge of the microbiome has led to significant advancements in the agrifood system. Case studies based on microbiome applications have been reported worldwide and, in this review, we have selected 14 success stories that showcase the imp...
Connectivity characterization of the mouse basolateral amygdalar complex
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 12, Iss 1, Pp 1-25 (2021)
Abstract: The basolateral amygdala is implicated in several behavior-related states including anxiety, autism, and addiction. The authors apply circuit-level pathway tracing methods combined with computational techniques to provide a comprehensive connectivity a...