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Advanced Search Results For "Creighton A"

1 - 10 of 12,139 results for
 "Creighton A"
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Analysis of Canadian and Irish forage, oats and commercially available equine concentrate feed for pathogenic fungi and mycotoxins

Publication Type:Academic Journal

Source(s):Irish Veterinary Journal, Vol 60, Iss 4, Pp 231-236 (2007)

Abstract:Abstract Respiratory infections, recurrent airway obstruction (RAO) and exercise induced pulmonary haemorrhage (EIPH) are major causes of poor performance in horses. Fungi and mycotoxins are now recognised as a major cause of these conditions. The most...

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Characterization of basal ganglia volume changes in the context of HIV and polysubstance use

Publication Type:Academic Journal

Source(s):Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)

Abstract:Abstract HIV and psychoactive substances can impact the integrity of the basal ganglia (BG), a neural substrate of cognition, motor control, and reward-seeking behaviors. This study assessed BG gray matter (GM) volume as a function of polysubstance (st...

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WIN site inhibition disrupts a subset of WDR5 function

Publication Type:Academic Journal

Source(s):Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)

Abstract:Abstract WDR5 nucleates the assembly of histone-modifying complexes and acts outside this context in a range of chromatin-centric processes. WDR5 is also a prominent target for pharmacological inhibition in cancer. Small-molecule degraders of WDR5 have...

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Global molecular alterations involving recurrence or progression of pediatric brain tumors

Publication Type:Academic Journal

Source(s):Neoplasia: An International Journal for Oncology Research, Vol 24, Iss 1, Pp 22-33 (2022)

Abstract:Background: We aimed to identify molecular changes in recurrent or progressive pediatric brain tumors, as compared to the corresponding initial tumors from the same patients, using genomic, transcriptomic, and proteomic data from a unique and large coh...

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MAPK4 promotes triple negative breast cancer growth and reduces tumor sensitivity to PI3K blockade

Publication Type:Academic Journal

Source(s):Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

Abstract:PI3K inhibitors have limited efficacy in triple negative breast cancer (TNBC). Here, the authors show that MAPK4 activates AKT independent of PI3K and thus promotes tumour growth in a subset of TNBC and that MAPK4 inhibition sensitizes to PI3K blockade...

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CKB inhibits epithelial-mesenchymal transition and prostate cancer progression by sequestering and inhibiting AKT activation

Publication Type:Academic Journal

Source(s):Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 11, Pp 1147-1165 (2021)

Abstract:Epithelial-mesenchymal transition (EMT) contributes to tumor invasion, metastasis and drug resistance. AKT activation is key in a number of cellular processes. While many positive regulators for either EMT or AKT activation have been reported, few nega...

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The EMT activator ZEB1 accelerates endosomal trafficking to establish a polarity axis in lung adenocarcinoma cells

Publication Type:Academic Journal

Source(s):Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)

Abstract:The way in which metastatic tumour cells control endocytic vesicular trafficking networks to establish a front-rear polarity axis that facilitates motility remains unclear. Here, the authors show that the EMT activator ZEB1 influences vesicular traffic...

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Participatory research with a rural Aboriginal Community Controlled Health Organisation: lessons learned using the CONSIDER statement

Publication Type:Academic Journal

Source(s):Rural and Remote Health, Vol 22 (2022)

Abstract:Context: In Australia, Aboriginal Community Controlled Health Organisations (ACCHOs) are geographically proximal to where Aboriginal and Torres Strait Islander People reside and are valued for providing holistic and culturally safe primary health care....

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Three dimensional printing of a low‐cost middle‐ear training model for surgical management of otosclerosis

Publication Type:Academic Journal

Source(s):Laryngoscope Investigative Otolaryngology, Vol 6, Iss 5, Pp 1133-1136 (2021)

Abstract:Abstract Background Surgical management of otosclerosis is technically challenging with studies demonstrating that outcomes are commensurate with surgical experience. Moreover, experts apply less force on the ossicular chain during prosthesis placement...

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Tracking implementation within a community-led whole of system approach to address childhood overweight and obesity in south west Sydney, Australia

Publication Type:Academic Journal

Source(s):BMC Public Health, Vol 21, Iss 1, Pp 1-11 (2021)

Abstract:Abstract Background Obesity is a chronic disease that contributes to additional comorbidities including diabetes, kidney disease and several cancers. Change4Campbelltown implemented a ‘whole of system’ approach to address childhood overweight and obesi...

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