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Advanced Search Results For "Davis, Ashley T."

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 "Davis, Ashley T."
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Small RNA pathways in the nematode Ascaris in the absence of piRNAs

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)

Abstract: The parasitic nematode Ascaris lacks piRNAs. Here the authors compare Argonaute proteins and small RNAs from C. elegans and Ascaris, expanding our understanding of the conservation, divergence, and flexibility of Argonautes and small RNA pathways in ne...

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PET Imaging of [11C]MPC-6827, a Microtubule-Based Radiotracer in Non-Human Primate Brains

Publication Type: Academic Journal

Source(s): Molecules, Vol 25, Iss 2289, p 2289 (2020)

Abstract: Dysregulation of microtubules is commonly associated with several psychiatric and neurological disorders, including addiction and Alzheimer’s disease. Imaging of microtubules in vivo using positron emission tomography (PET) could provide valuable infor...

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Delayed effects of radiation in adipose tissue reflect progenitor damage and not cellular senescence

Publication Type: Periodical

Source(s): GeroScience; 20220101, Issue: Preprints p1-15, 15p

Abstract: The pathogenesis of many age-related diseases is linked to cellular senescence, a state of inflammation-inducing, irreversible cell cycle arrest. The consequences and mechanisms of age-associated cellular senescence are often studied using in vivo mode...

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A Low Iron Diet Protects from Steatohepatitis in a Mouse Model

Publication Type: Academic Journal

Source(s): Nutrients, Vol 11, Iss 9, p 2172 (2019)

Abstract: High tissue iron levels are a risk factor for multiple chronic diseases including type 2 diabetes mellitus (T2DM) and non-alcoholic fatty liver disease (NAFLD). To investigate causal relationships and underlying mechanisms, we used an established NAFLD...

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Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

Publication Type: Academic Journal

Source(s): The Lancet Global Health, Vol 10, Iss 7, Pp e1003-e1011 (2022)

Abstract: Summary: Background: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of ...

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National identity predicts public health support during a global pandemic

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

Abstract: Understanding collective behaviour is an important aspect of managing the pandemic response. Here the authors show in a large global study that participants that reported identifying more strongly with their nation reported greater engagement in public...

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Neurologic Manifestations of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Hospitalized Patients During the First Year of the COVID-19 Pandemic

Publication Type: Academic Journal

Source(s): Critical Care Explorations, Vol 4, Iss 4, p e0686 (2022)

Abstract: OBJECTIVES:. To describe the prevalence, associated risk factors, and outcomes of serious neurologic manifestations (encephalopathy, stroke, seizure, and meningitis/encephalitis) among patients hospitalized with severe acute respiratory syndrome corona...

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Phylogenomic Diversity Elucidates Mechanistic Insights into Lyme Borreliae-Host Association

Publication Type: Academic Journal

Source(s): mSystems, Vol 7, Iss 4 (2022)

Abstract: ABSTRACT Host association—the selective adaptation of pathogens to specific host species—evolves through constant interactions between host and pathogens, leaving a lot yet to be discovered on immunological mechanisms and genomic determinants. The caus...

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Detection of COVID-19 using multimodal data from a wearable device: results from the first TemPredict Study

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)

Abstract: Abstract Early detection of diseases such as COVID-19 could be a critical tool in reducing disease transmission by helping individuals recognize when they should self-isolate, seek testing, and obtain early medical intervention. Consumer wearable devic...

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Optimization of methods for the accurate characterization of whole blood neutrophils

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)

Abstract: Abstract Neutrophils are the most abundant circulating leukocyte population with critical roles in immune defense, regulation of innate and adaptive immune systems, and disease pathogenesis. Our progress in understanding precise mechanisms of neutrophi...

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