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Advanced Search Results For "Douville C"

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 "Douville C"
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Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

Publication Type: Academic Journal

Source(s): Cell Genomics, Vol 3, Iss 1, Pp 100241- (2023)

Abstract: Summary: Polygenic risk scores (PRSs) have been widely explored in precision medicine. However, few studies have thoroughly investigated their best practices in global populations across different diseases. We here utilized data from Global Biobank Met...

Contrasted release of insoluble elements (Fe, Al, rare earth elements, Th, Pa) after dust deposition in seawater: a tank experiment approach

Publication Type: Academic Journal

Source(s): Biogeosciences, Vol 18, Pp 2663-2678 (2021)

Abstract: Lithogenic elements such as aluminum (Al), iron (Fe), rare earth elements (REEs), thorium (232Th and 230Th, given as Th) and protactinium (Pa) are often assumed to be insoluble. In this study, their dissolution from Saharan dust reaching Mediterranean ...

Pembrolizumab for patients with leptomeningeal metastasis from solid tumors: efficacy, safety, and cerebrospinal fluid biomarkers

Publication Type: Academic Journal

Source(s): Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)

Abstract: Background The benefit of immune checkpoint inhibitors (ICIs) in patients with leptomeningeal metastases (LMM) is unknown.Methods We undertook a phase II trial of pembrolizumab in patients with LMM from solid tumors. Eligible patients had radiologic/cy...

Severe Acute Respiratory Syndrome Coronavirus 2 Prevalence, Seroprevalence, and Exposure among Evacuees from Wuhan, China, 2020

Publication Type: Academic Journal

Source(s): Emerging Infectious Diseases, Vol 26, Iss 9, Pp 1998-2004 (2020)

Abstract: To determine prevalence of, seroprevalence of, and potential exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among a cohort of evacuees returning to the United States from Wuhan, China, in January 2020, we conducted a cross-sec...

Clouds damp the radiative impacts of polar sea ice loss

Publication Type: Academic Journal

Source(s): The Cryosphere, Vol 14, Pp 2673-2686 (2020)

Abstract: Clouds play an important role in the climate system: (1) cooling Earth by reflecting incoming sunlight to space and (2) warming Earth by reducing thermal energy loss to space. Cloud radiative effects are especially important in polar regions and have t...

Tracking Changes in Climate Sensitivity in CNRM Climate Models

Publication Type: Academic Journal

Source(s): Journal of Advances in Modeling Earth Systems, Vol 13, Iss 6, Pp n/a-n/a (2021)

Abstract: Abstract The equilibrium climate sensitivity (ECS) in the latest version of CNRM climate model, CNRM‐CM6‐1, and in its high‐resolution counterpart, CNRM‐CM6‐1‐HR, is significantly larger than in the previous version (CNRM‐CM5.1). The traceability of th...

Evaluation of CMIP6 DECK Experiments With CNRM‐CM6‐1

Publication Type: Academic Journal

Source(s): Journal of Advances in Modeling Earth Systems, Vol 11, Iss 7, Pp 2177-2213 (2019)

Abstract: Abstract This paper describes the main characteristics of CNRM‐CM6‐1, the fully coupled atmosphere‐ocean general circulation model of sixth generation jointly developed by Centre National de Recherches Météorologiques (CNRM) and Cerfacs for the sixth p...

Exploring the Grid Value of Offshore Wind Energy in Oregon

Publication Type: Academic Journal

Source(s): Energies, Vol 14, Iss 4435, p 4435 (2021)

Abstract: The significant offshore wind energy potential of Oregon faces several challenges, including a power grid which was not developed for the purpose of transmitting energy from the ocean. The grid impacts of the energy resource are considered through the ...

Surface ocean pH variations since 1689 CE and recent ocean acidification in the tropical South Pacific

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)

Abstract: Ocean acidification due to the industrial era is a major marine environmental concern, yet little is known on the historical ocean pH changes prior to human influence. Here, Wu et al. show that tropical South Pacific seawater pH is linked to ENSO pacin...

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The Cloud Feedback Model Intercomparison Project (CFMIP) contribution to CMIP6

Publication Type: Academic Journal

Source(s): Geoscientific Model Development, Vol 10, Iss 1, Pp 359-384 (2017)

Abstract: The primary objective of CFMIP is to inform future assessments of cloud feedbacks through improved understanding of cloud–climate feedback mechanisms and better evaluation of cloud processes and cloud feedbacks in climate models. However, the CFMIP app...

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