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Advanced Search Results For "Eric Lam, F. Y."

1 - 10 of 341 results for
 "Eric Lam, F. Y."
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Genetic Testing and Its Clinical Application in Prostate Cancer Management: Consensus Statements from the Hong Kong Urological Association and Hong Kong Society of Uro-Oncology

Publication Type:Academic Journal

Source(s):Frontiers in Oncology, Vol 12 (2022)

Abstract:BackgroundIn recent years, indications for genetic testing in prostate cancer (PC) have expanded from patients with a family history of prostate and/or related cancers to those with advanced castration-resistant disease, and even to early PC patients f...

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Open data from the first and second observing runs of Advanced LIGO and Advanced Virgo

Publication Type:Academic Journal

Source(s):SoftwareX, Vol 13, Iss , Pp 100658- (2021)

Abstract:Advanced LIGO and Advanced Virgo are monitoring the sky and collecting gravitational-wave strain data with sufficient sensitivity to detect signals routinely. In this paper we describe the data recorded by these instruments during their first and secon...

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Burden of hereditary cancer susceptibility in unselected patients with pancreatic ductal adenocarcinoma referred for germline screening

Publication Type:Academic Journal

Source(s):Cancer Medicine, Vol 9, Iss 11, Pp 4004-4013 (2020)

Abstract:Abstract Background Recent guidelines recommend consideration of germline testing for all newly diagnosed pancreatic ductal adenocarcinoma (PDAC). The primary aim of this study was to determine the burden of hereditary cancer susceptibility in PDAC. A ...

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Expression-Based Cell Lineage Analysis in Drosophila Through a Course-Based Research Experience for Early Undergraduates

Publication Type:Academic Journal

Source(s):G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3791-3800 (2019)

Abstract:A variety of genetic techniques have been devised to determine cell lineage relationships during tissue development. Some of these systems monitor cell lineages spatially and/or temporally without regard to gene expression by the cells, whereas others ...

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Publisher Correction: Shared heritability and functional enrichment across six solid cancers

Publication Type:Academic Journal

Source(s):Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)

Abstract:An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Shared heritability and functional enrichment across six solid cancers

Publication Type:Academic Journal

Source(s):Nature Communications, Vol 10, Iss 1, Pp 1-23 (2019)

Abstract:Similarities in cancers can be studied to interrogate their etiology. Here, the authors use genome-wide association study summary statistics from six cancer types based on 296,215 cases and 301,319 controls of European ancestry, showing that solid tumo...

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Targeting SPINK1 in the damaged tumour microenvironment alleviates therapeutic resistance

Publication Type:Academic Journal

Source(s):Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)

Abstract:Tumour microenvironment actively contributes to drug resistance in clinical oncology. Here, the authors show that genotoxic stress induces senescence in human stromal cells, which in turn secrete serine protease inhibitor Kazal type 1 (SPINK1) and prom...

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The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1

Publication Type:Academic Journal

Source(s):Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)

Abstract:In cancer the side effects of therapeutic agents can provoke senescence-associated secretory phenotype (SASP), which can drive cancer resistance. During the DNA damage response, transcription factor Zscan4 expression is elevated by an ATM-TRAF6-TAK1 ax...

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The mediating factors in the relationship between lower urinary tract symptoms and health-related quality of life

Publication Type:Academic Journal

Source(s):BMC Research Notes, Vol 10, Iss 1, Pp 1-8 (2017)

Abstract:Abstract Objectives An earlier study found that mental health partially mediates the relationship between lower urinary tract symptoms (LUTS) severity and health-related quality of life (HRQOL). In other words, LUTS adversely affects mental health, whi...

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World Congress Integrative Medicine & Health 2017: part two

Publication Type:Academic Journal

Source(s):BMC Complementary and Alternative Medicine, Vol 17, Iss S1, Pp 1-65 (2017)

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