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L1077P CFTR pathogenic variant function rescue by Elexacaftor–Tezacaftor–Ivacaftor in cystic fibrosis patient-derived air–liquid interface (ALI) cultures and organoids: in vitro guided personalized therapy of non-F508del patients
Publication Type: Academic Journal
Source(s): Respiratory Research, Vol 24, Iss 1, Pp 1-20 (2023)
Abstract: Abstract Cystic fibrosis (CF) is caused by defects of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. CFTR-modulating drugs may overcome specific defects, such as the case of Trikafta, which is a clinically approved triple combinat...
Correction to: L1077P CFTR pathogenic variant function rescue by Elexacaftor–Tezacaftor–Ivacaftor in cystic fbrosis patient-derived air–liquid interface (ALI) cultures and organoids: in vitro guided personalized therapy of non-F508del patients
Publication Type: Academic Journal
Source(s): Respiratory Research, Vol 24, Iss 1, Pp 1-2 (2023)
Evaluation of Soil Heavy Metal Contamination and Potential Human Health Risk inside Forests, Wildfire Forests and Urban Areas
Publication Type: Academic Journal
Source(s): Environments, Vol 10, Iss 146, p 146 (2023)
Abstract: Recently, due to rapid industrialization and urbanization, many studies have focused on the assessment of soil metal contamination. The present research aimed to investigate the concentration of potentially hazardous elements (Al, Cr, Cu, Fe, Mg, Mn, N...
Organic Electrochemical Transistor Immuno-Sensors for Spike Protein Early Detection
Publication Type: Academic Journal
Source(s): Biosensors, Vol 13, Iss 739, p 739 (2023)
Abstract: The global COVID-19 pandemic has had severe consequences from the social and economic perspectives, compelling the scientific community to focus on the development of effective diagnostics that can combine a fast response and accurate sensitivity/speci...
The STING/TBK1/IRF3/IFN type I pathway is defective in cystic fibrosis
Publication Type: Academic Journal
Source(s): Frontiers in Immunology, Vol 14 (2023)
Abstract: Cystic fibrosis (CF) is a rare autosomal recessive disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The most common mutation is F508del-CFTR (ΔF) which leads the encoded ion channel towards misfolding ...
Comparative Analysis of a Human Neutralizing mAb Specific for SARS-CoV-2 Spike-RBD with Cilgavimab and Tixagevimab for the Efficacy on the Omicron Variant in Neutralizing and Detection Assays.
Publication Type: Academic Journal
Source(s): International Journal of Molecular Sciences. Jun2023, Vol. 24 Issue 12, p10053. 17p.
Abstract: The recent pandemic years have prompted the scientific community to increasingly search for and adopt new and more efficient therapeutic and diagnostic approaches to deal with a new infection. In addition to the development of vaccines, which has playe...
Comparative Analysis of a Human Neutralizing mAb Specific for SARS-CoV-2 Spike-RBD with Cilgavimab and Tixagevimab for the Efficacy on the Omicron Variant in Neutralizing and Detection Assays
Publication Type: Academic Journal
Source(s): International Journal of Molecular Sciences, Vol 24, Iss 10053, p 10053 (2023)
Abstract: The recent pandemic years have prompted the scientific community to increasingly search for and adopt new and more efficient therapeutic and diagnostic approaches to deal with a new infection. In addition to the development of vaccines, which has playe...
The Immune Response to SARS-CoV-2 Vaccine in a Cohort of Family Pediatricians from Southern Italy
Publication Type: Academic Journal
Source(s): Cells, Vol 12, Iss 1447, p 1447 (2023)
Abstract: In Italy, from January 2021, the Ministry of Health indicated a vaccination plan against COVID for frail patients and physicians based on a three-dose scheme. However, conflicting results have been reported on which biomarkers permit immunization asses...
Immuno-Sensing at Ultra-Low Concentration of TG2 Protein by Organic Electrochemical Transistors
Publication Type: Academic Journal
Source(s): Biosensors, Vol 13, Iss 448, p 448 (2023)
Abstract: Transglutaminase 2 (TG2) is a ubiquitously expressed member of the transglutaminase family with Ca2+-dependent protein crosslinking activity. Its subcellular localization is crucial in determining its function, and indeed, TG2 is found in the extracell...
Organic Electrochemical Transistor Immuno-Sensors for Spike Protein Early Detection.
Publication Type: Academic Journal
Source(s): Biosensors (2079-6374); Jul2023, Vol. 13 Issue 7, p739, 13p
Abstract: Copyright of Biosensors (2079-6374) is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email a...