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Family Aggregation of Hematological Malignancies Discovered from an Acute Myeloid Leukemia Patient with STK11 and THBD Gene Mutation
Publication Type: Academic Journal
Source(s): Case Reports in Oncology, Vol 16, Iss 1, Pp 734-738 (2023)
Abstract: Acute myeloid leukemia (AML) is a large class of heterogeneous hematological malignancies with the highest incidence rate in acute leukemia. Its pathogenesis is still unclear, which may be related to genetics. According to the latest AML NCCN guideline...
Comparison Study of the Metabolic Characteristics of Three Kinds of Deuterium-labeled Glucose in Rat Glioma Cells
Publication Type: Academic Journal
Source(s): Chinese Journal of Magnetic Resonance, Vol 40, Iss 03, Pp 239-245 (2023)
Abstract: Deuterium (2H) magnetic resonance imaging is an emerging molecular metabolic imaging method that can visualize the metabolic pathway in vivo, and therefore has great potential in clinical applications such as cancer detection. In this work, we aimed to...
IGF2BP3 promotes the progression of colorectal cancer and mediates cetuximab resistance by stabilizing EGFR mRNA in an m6A-dependent manner
Publication Type: Academic Journal
Source(s): Cell Death and Disease, Vol 14, Iss 9, Pp 1-13 (2023)
Abstract: Abstract Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3), an RNA-binding protein, is associated with tumorigenesis and progression. However, the exact molecular mechanisms of IGF2BP3 in colorectal cancer (CRC) oncogenesis, progression, an...
Treatment effects after maxillary expansion using invisalign first system vs. acrylic splint expander in mixed dentition: a prospective cohort study
Publication Type: Academic Journal
Source(s): BMC Oral Health, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract: Abstract Background Invisalign First System (First) is a new type of orthodontic appliance for maxillary arch expansion in mixed dentition children. Till now, few studies have evaluated the expansion effects of First versus other appliances. What’s mor...
Rational application of EGFR-TKI adjuvant therapy in patients with completely resected stage IB-IIIA EGFR-mutant NSCLC: a systematic review and meta-analysis of 11 randomized controlled trials
Publication Type: Academic Journal
Source(s): BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract: Abstract Purpose To determine the role and rational application of epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) adjuvant therapy in patients with completely resected stage IB-IIIA EGFR-mutant non-small-cell lung cancer (NSCLC)....
Molecular subtypes predict therapeutic responses and identifying and validating diagnostic signatures based on machine learning in chronic myeloid leukemia
Publication Type: Academic Journal
Source(s): Cancer Cell International, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract: Abstract Chronic myeloid leukemia (CML) is a hematological tumor derived from hematopoietic stem cells. The aim of this study is to analyze the biological characteristics and identify the diagnostic markers of CML. We obtained the expression profiles f...
Efficacy and safety of glucocorticoid in the treatment of sepsis: A systematic review and meta-analysis
Publication Type: Academic Journal
Source(s): Asian Journal of Surgery, Vol 46, Iss 7, Pp 2912-2914 (2023)
Histopathology images predict multi-omics aberrations and prognoses in colorectal cancer patients
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract: Abstract Histopathologic assessment is indispensable for diagnosing colorectal cancer (CRC). However, manual evaluation of the diseased tissues under the microscope cannot reliably inform patient prognosis or genomic variations crucial for treatment se...
Morphological changes in alveolar bone thickness and height after orthodontic proclination or labial movement combined with autogenous soft tissue grafting: a CBCT evaluation
Publication Type: Academic Journal
Source(s): BMC Oral Health, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract: Abstract Background Autogenous soft tissue grafting is indicated in thin gingival biotypes before orthodontic proclination or labial movements to increase the keratinized gingiva and prevent gingival recession. However, its effect on local alveolar bon...
Lymph node metastasis in oral squamous cell carcinoma: Where we are and where we are going
Publication Type: Academic Journal
Source(s): Clinical and Translational Discovery, Vol 3, Iss 4, Pp n/a-n/a (2023)
Abstract: Abstract Background Oral cancer is a common malignant tumour in the head and neck region, with over 90% of cases being oral squamous cell carcinoma (OSCC). Lymph node metastasis (LNM) is a significant adverse prognostic factor in OSCC; however, the mec...