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Circulating Th17 T cells at treatment onset predict autoimmune toxicity of PI3Kδ inhibitors
Publication Type: Academic Journal
Source(s): Blood Cancer Journal, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract: Abstract PI3Kδ inhibitors are approved for the therapy of B cell malignancies, but their clinical use has been limited by unpredictable autoimmune toxicity, despite promising efficacy and evidence that toxicity is associated with improved clinical outc...
Associations of sNfL with clinico‐radiological measures in a large MS population
Publication Type: Academic Journal
Source(s): Annals of Clinical and Translational Neurology, Vol 10, Iss 1, Pp 84-97 (2023)
Abstract: Abstract Objective Evaluation of serum neurofilament light chain (sNfL), measured using high‐throughput assays on widely accessible platforms in large, real‐world MS populations, is a critical step for sNfL to be utilized in clinical practice. Methods ...
Exploring bias in the OCO-3 snapshot area mapping mode via geometry, surface, and aerosol effects
Publication Type: Academic Journal
Source(s): Atmospheric Measurement Techniques, Vol 16, Pp 109-133 (2023)
Abstract: The Atmospheric Carbon Observations from Space (ACOS) retrieval algorithm has been delivering operational column-averaged carbon dioxide dry-air mole fraction (XCO2) data for the Orbiting Carbon Observatory (OCO) missions since 2014. The ACOS Le...
Evaluation of the Access Bio CareStart rapid SARS-CoV-2 antigen test in asymptomatic individuals tested at a community mass-testing program in Western Massachusetts
Publication Type: Academic Journal
Source(s): Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract: Abstract Point-of-care antigen-detecting rapid diagnostic tests (RDTs) to detect Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) represent a scalable tool for surveillance of active SARS-CoV-2 infections in the population. Data on the perf...
Erratum to: Searches for long-lived charged particles in pp collisions at s $$ \sqrt{\textrm{s}} $$ = 7 and 8 TeV
Publication Type: Academic Journal
Source(s): Journal of High Energy Physics, Vol 2022, Iss 11, Pp 1-26 (2022)
Measurement of the polarisation of single top quarks and antiquarks produced in the t-channel at s $$ \sqrt{s} $$ = 13 TeV and bounds on the tWb dipole operator from the ATLAS experiment
Publication Type: Academic Journal
Source(s): Journal of High Energy Physics, Vol 2022, Iss 11, Pp 1-62 (2022)
Abstract: Abstract A simultaneous measurement of the three components of the top-quark and top-antiquark polarisation vectors in t-channel single-top-quark production is presented. This analysis is based on data from proton–proton collisions at a centre-of-mass ...
Search for type-III seesaw heavy leptons in leptonic final states in pp collisions at $$\sqrt{s} = 13~\text {TeV}$$ s = 13 TeV with the ATLAS detector
Publication Type: Academic Journal
Source(s): European Physical Journal C: Particles and Fields, Vol 82, Iss 11, Pp 1-30 (2022)
Abstract: Abstract A search for the pair production of heavy leptons as predicted by the type-III seesaw mechanism is presented. The search uses proton–proton collision data at a centre-of-mass energy of 13 TeV, corresponding to $$139\,\text {fb}^{-1}$$ 139 fb -...
Clinical practice guideline recommendation summaries for pediatric oncology health care professionals: A qualitative study.
Publication Type: Academic Journal
Source(s): PLoS ONE, Vol 18, Iss 2, p e0281890 (2023)
Abstract: ObjectiveTo develop a summary format of clinical practice guideline (CPG) recommendations to improve understandability among health care professionals.MethodsWe developed a summary format based on current research and used the "Think Aloud" technique i...
Investigating mitochondrial fission, fusion, and autophagy in retinal pigment epithelium from donors with age-related macular degeneration
Publication Type: Academic Journal
Source(s): Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract: Abstract Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in developed countries, characterized by the death of retinal pigment epithelial (RPE) cells and photoreceptors. Previous studies report an accumulation of d...
Atmospheric methane isotopes identify inventory knowledge gaps in the Surat Basin, Australia, coal seam gas and agricultural regions
Publication Type: Academic Journal
Source(s): Atmospheric Chemistry and Physics, Vol 22, Pp 15527-15558 (2022)
Abstract: In-flight measurements of atmospheric methane (CH4(a)) and mass balance flux quantification studies can assist with verification and improvement in the UNFCCC National Inventory reported CH4 emissions. In the Surat Basin gas fields, Queensland, Austral...