Publication Type:Academic Journal

Source(s):Cell Reports, Vol 39, Iss 7, Pp 110812- (2022)

Abstract:Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal antibodies (mAbs) can reduce the risk of hospitalization from coronavirus disease 2019 (COVID-19) when administered early. However, SARS-CoV-2 variants of con...

Publication Type:Academic Journal

Source(s):Mountain Research and Development, Vol 41, Iss 3, Pp D1-D11 (2021)

Abstract:In 2018, Jackson Hole Mountain Resort (JHMR) in Teton Village, WY, USA, discontinued its International Standards Organization 14001 environmental management system. JHMR needed a replacement voluntary environmental program (VEP) that would empower reso...

Publication Type:Academic Journal

Source(s):Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)

Abstract:Safely opening university campuses has been a major challenge during the COVID-19 pandemic. Here, the authors describe a program of public health measures employed at a university in the United States which, combined with other non-pharmaceutical inter...

Publication Type:Academic Journal

Source(s):The Lancet Global Health, Vol 10, Iss 7, Pp e1003-e1011 (2022)

Abstract:Summary: Background: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of ...

Publication Type:Academic Journal

Source(s):Frontiers in Psychiatry, Vol 13 (2022)

Abstract:PurposeTo assess the pathological aging effect on caudate functional connectivity among mild cognitive impairment (MCI) participants and examine whether and how sex and amyloid contribute to this process.Materials and MethodsTwo hundred and seventy-sev...

Publication Type:Academic Journal

Source(s):The Lancet: Digital Health, Vol 4, Iss 4, Pp e220-e234 (2022)

Abstract:Summary: Background: Dexamethasone was the first intervention proven to reduce mortality in patients with COVID-19 being treated in hospital. We aimed to evaluate the adoption of corticosteroids in the treatment of COVID-19 in the UK after the RECOVERY...

Publication Type:Academic Journal

Source(s):iScience, Vol 24, Iss 11, Pp 103353- (2021)

Abstract:Summary: We identify amino acid variants within dominant SARS-CoV-2 T cell epitopes by interrogating global sequence data. Several variants within nucleocapsid and ORF3a epitopes have arisen independently in multiple lineages and result in loss of reco...

Publication Type:Academic Journal

Source(s):Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)

Abstract:Prostate cancer cells depend on MTAP, the rate-limiting enzyme involved in the methionine salvage pathway, to cope with increased polyamine biosynthesis. Here, the authors show that inducing upregulation of polyamine biosynthesis and targeting MTAP syn...

Publication Type:Academic Journal

Source(s):Frontiers in Immunology, Vol 11 (2020)

Abstract:Conventional vaccine design has been based on trial-and-error approaches, which have been generally successful. However, there have been some major failures in vaccine development and we still do not have highly effective licensed vaccines for tubercul...

Publication Type:Academic Journal

Source(s):Mountain Research & Development. Aug2021, Vol. 41 Issue 3, pD1-D11. 11p.

Abstract:In 2018, Jackson Hole Mountain Resort (JHMR) in Teton Village, WY, USA, discontinued its International Standards Organization 14001 environmental management system. JHMR needed a replacement voluntary environmental program (VEP) that would empower reso...