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Advanced Search Results For "Gallagher, Tim"

1 - 10 of 544 results for
 "Gallagher, Tim"
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Association of body mass index with outcomes in patients with newly diagnosed atrial fibrillation: GARFIELD-AF

Publication Type:Academic Journal

Source(s):Open Heart, Vol 9, Iss 2 (2022)

Abstract:Objective While greater body mass index (BMI) is associated with increased risk of developing atrial fibrillation (AF), the impact of BMI on outcomes in newly diagnosed AF is unclear. We examine the influence of BMI on outcomes and whether this is modi...

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Persistent organic pollutants and risk of cutaneous malignant melanoma among women

Publication Type:Academic Journal

Source(s):Cancer Reports, Vol 5, Iss 8, Pp n/a-n/a (2022)

Abstract:Abstract Background Despite the increasing trend of cutaneous malignant melanoma (CMM) incidence in Canada, especially among females, few risk factors other than ultraviolet radiation exposure, have been identified. Aim We conducted a case–control stud...

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The WIRE study a phase II, multi-arm, multi-centre, non-randomised window-of-opportunity clinical trial platform using a Bayesian adaptive design for proof-of-mechanism of novel treatment strategies in operable renal cell cancer – a study protocol

Publication Type:Academic Journal

Source(s):BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)

Abstract:Abstract Background Window-of-opportunity trials, evaluating the engagement of drugs with their biological target in the time period between diagnosis and standard-of-care treatment, can help prioritise promising new systemic treatments for later-phase...

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Age-Related Variation in the Provision of Primary Care Services and Medication Prescriptions for Patients with Cardiovascular Disease

Publication Type:Academic Journal

Source(s):International Journal of Environmental Research and Public Health, Vol 19, Iss 10761, p 10761 (2022)

Abstract:As population aging progresses, demands of patients with cardiovascular diseases (CVD) on the primary care services is inevitably increased. However, the utilisation of primary care services across varying age groups is unknown. The study aims to explo...

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The impact of viral mutations on recognition by SARS-CoV-2 specific T cells

Publication Type:Academic Journal

Source(s):iScience, Vol 24, Iss 11, Pp 103353- (2021)

Abstract:Summary: We identify amino acid variants within dominant SARS-CoV-2 T cell epitopes by interrogating global sequence data. Several variants within nucleocapsid and ORF3a epitopes have arisen independently in multiple lineages and result in loss of reco...

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The Impact of Intracoronary Imaging on PCI Outcomes in Cases Utilising Rotational Atherectomy: An Analysis of 8,417 Rotational Atherectomy Cases from the British Cardiovascular Intervention Society Database

Publication Type:Academic Journal

Source(s):Journal of Interventional Cardiology, Vol 2022 (2022)

Abstract:Introduction. There is increasing evidence supporting the use of intracoronary imaging to optimize the outcomes of percutaneous coronary intervention (PCI). However, there are no studies examining the impact of imaging on PCI outcomes in cases utilisin...

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Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7

Publication Type:Academic Journal

Source(s):Cell Reports, Vol 35, Iss 13, Pp 109292- (2021)

Abstract:Summary: We report severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ΔH69/V70 in multiple independent lineages, often occurring after acquisition of receptor binding motif replacements such as N439K and Y453F, known to increase binding...

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Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study

Publication Type:Academic Journal

Source(s):The Lancet Public Health, Vol 6, Iss 5, Pp e335-e345 (2021)

Abstract:Summary: Background: The SARS-CoV-2 variant B.1.1.7 was first identified in December, 2020, in England. We aimed to investigate whether increases in the proportion of infections with this variant are associated with differences in symptoms or disease c...

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Hyperpolarized 13C-Pyruvate Metabolism as a Surrogate for Tumor Grade and Poor Outcome in Renal Cell Carcinoma—A Proof of Principle Study

Publication Type:Academic Journal

Source(s):Cancers, Vol 14, Iss 335, p 335 (2022)

Abstract:Differentiating aggressive clear cell renal cell carcinoma (ccRCC) from indolent lesions is challenging using conventional imaging. This work prospectively compared the metabolic imaging phenotype of renal tumors using carbon-13 MRI following injection...

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Development of a Core outcome set for fetal Myelomeningocele (COSMiC): study protocol

Publication Type:Academic Journal

Source(s):Trials, Vol 21, Iss 1, Pp 1-6 (2020)

Abstract:Abstract Background Open spina bifida (OSB) is one of the most common congenital central nervous system defects and leads to long-term physical and cognitive disabilities. Open fetal surgery for OSB improves neurological outcomes and reduces the need f...

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