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Advanced Search Results For "Goes, Fernando S."

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 "Goes, Fernando S."
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Identifying the Common Genetic Basis of Antidepressant Response

Publication Type: Academic Journal

Source(s): Biological Psychiatry Global Open Science, Vol 2, Iss 2, Pp 115-126 (2022)

Abstract: Background: Antidepressants are a first-line treatment for depression. However, only a third of individuals experience remission after the first treatment. Common genetic variation, in part, likely regulates antidepressant response, yet the success of ...

Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients

Publication Type: Academic Journal

Source(s): Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)

Abstract: Abstract Lithium is the gold standard therapy for Bipolar Disorder (BD) but its effectiveness differs widely between individuals. The molecular mechanisms underlying treatment response heterogeneity are not well understood, and personalized treatment i...

HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disorders

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)

Abstract: Abstract Bipolar affective disorder (BD) is a severe psychiatric illness, for which lithium (Li) is the gold standard for acute and maintenance therapies. The therapeutic response to Li in BD is heterogeneous and reliable biomarkers allowing patients s...


A 7 Tesla Amygdalar-Hippocampal Shape Analysis of Lithium Response in Bipolar Disorder

Publication Type: Academic Journal

Source(s): Frontiers in Psychiatry, Vol 12 (2021)

Abstract: Research to discover clinically useful predictors of lithium response in patients with bipolar disorder has largely found them to be elusive. We demonstrate here that detailed neuroimaging may have the potential to fill this important gap in mood disor...

Genome-wide significant risk loci for mood disorders in the Old Order Amish founder population

Publication Type: Periodical

Source(s): Molecular Psychiatry; 20230101, Issue: Preprints p1-10, 10p

Abstract: Genome-wide association studies (GWAS) of mood disorders in large case-control cohorts have identified numerous risk loci, yet pathophysiological mechanisms remain elusive, primarily due to the very small effects of common variants. We sought to discov...

Investigating the phenotypic and genetic associations between personality traits and suicidal behavior across major mental health diagnoses.

Publication Type: Academic Journal

Source(s): European Archives of Psychiatry & Clinical Neuroscience; Dec2022, Vol. 272 Issue 8, p1611-1620, 10p, 1 Chart, 1 Graph

Abstract: Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. Ho...

Affected Sib-Pair Analyses Identify Signaling Networks Associated With Social Behavioral Deficits in Autism

Publication Type: Academic Journal

Source(s): Frontiers in Genetics, Vol 10 (2019)

Abstract: Autism spectrum disorders (ASDs) are characterized by deficits in three core behavioral domains: reciprocal social interactions, communication, and restricted interests and/or repetitive behaviors. Several hundreds of risk genes for autism have been id...

Neuroimaging Correlates of Depression after Traumatic Brain Injury: A Systematic Review.

Publication Type: Academic Journal

Source(s): Journal of Neurotrauma; Jun2022, Vol. 39 Issue 11/12, p755-772, 18p