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Advanced Search Results For "Goggins M"

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 "Goggins M"
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Endometrial gland-specific progestagenassociated endometrial protein and cilia gene splicing changes in recurrent pregnancy loss

Publication Type: Academic Journal

Source(s): Reproduction and Fertility, Vol 3, Iss 3, Pp 162-172 (2022)

Abstract: Endometrial glands are essential for fertility, consisting of ciliated and secretory cells that facilitate a suitable uterine environment for embryo implantation. This study sought to determine whether an endometrial gland-specific transcriptome and sp...

3D visualization of trans-syncytial nanopores provides a pathway for paracellular diffusion across the human placental syncytiotrophoblast

Publication Type: Academic Journal

Source(s): iScience, Vol 25, Iss 12, Pp 105453- (2022)

Abstract: Summary: The placental syncytiotrophoblast, a syncytium without cell-cell junctions, is the primary barrier between the mother and the fetus. Despite no apparent anatomical pathway for paracellular diffusion of solutes across the syncytiotrophoblast, s...

The effect of subjective social status on health-related quality of life decline in urban Chinese older adults: a four-year longitudinal study from Hong Kong

Publication Type: Academic Journal

Source(s): BMC Geriatrics, Vol 22, Iss 1, Pp 1-12 (2022)

Abstract: Abstract Background Improving health-related quality of life (HRQOL) is becoming a major focus of old age care and social policy. Researchers have been increasingly examining subjective social status (SSS), one’s self-perceived social position, as a pr...

Piloting a systems level intervention to improve cervical cancer screening, treatment and follow up in Kenya

Publication Type: Academic Journal

Source(s): Frontiers in Medicine, Vol 9 (2022)

Abstract: Although preventable, Cervical Cancer (CC) is the leading cause of cancer deaths among women in Sub-Saharan Africa with the highest incidence in East Africa. Kenyan guidelines recommend an immediate screen and treat approach using either Pap smear or v...

Metastatic gastroesophageal cancer in older patients – is this patient cohort represented in clinical trials?

Publication Type: Academic Journal

Source(s): BMC Cancer, Vol 22, Iss 1, Pp 1-9 (2022)

Abstract: Abstract Background Older patients are underrepresented in the clinical trials that determine the standards of care for oncological treatment. We conducted a review to identify whether there have been age-restrictive inclusion criteria in clinical tria...

Oil palm in the 2020s and beyond: challenges and solutions

Publication Type: Academic Journal

Source(s): CABI Agriculture and Bioscience, Vol 2, Iss 1, Pp 1-22 (2021)

Abstract: Abstract Background Oil palm, Elaeis guineensis, is by far the most important global oil crop, supplying about 40% of all traded vegetable oil. Palm oils are key dietary components consumed daily by over three billion people, mostly in Asia, and also h...

'Friendly reminder: hi! It is that time again ☺': understanding PMTCT care text message design preferences amongst pre- and post-partum women and their male partners

Publication Type: Academic Journal

Source(s): BMC Public Health, Vol 21, Iss 1, Pp 1-10 (2021)

Abstract: Abstract Background Prevention of mother-to-child HIV transmission (PMTCT) services in Kenya can be strengthened through the delivery of relevant and culturally appropriate SMS messages. Methods This study reports on the results of focus groups conduct...

Evaluation of an adapted version of the Diabetes Prevention Program for low- and middle-income countries: A cluster randomized trial to evaluate 'Lifestyle Africa' in South Africa.

Publication Type: Academic Journal

Source(s): PLoS Medicine, Vol 19, Iss 4, p e1003964 (2022)

Abstract: BackgroundLow- and middle-income countries (LMICs) are experiencing major increases in diabetes and cardiovascular conditions linked to overweight and obesity. Lifestyle interventions such as the United States National Diabetes Prevention Program (DPP)...


Genetic engineering of porcine endothelial cell lines for evaluation of human-to-pig xenoreactive immune responses

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Abstract: Abstract Xenotransplantation (cross-species transplantation) using genetically-engineered pig organs offers a potential solution to address persistent organ shortage. Current evaluation of porcine genetic modifications is to monitor the nonhuman primat...


Functional CDKN2A assay identifies frequent deleterious alleles misclassified as variants of uncertain significance

Publication Type: Academic Journal

Source(s): eLife, Vol 11 (2022)

Abstract: Pathogenic germline CDKN2A variants are associated with an increased risk of pancreatic ductal adenocarcinoma (PDAC). CDKN2A variants of uncertain significance (VUSs) are reported in up to 4.3% of patients with PDAC and result in significant uncertaint...