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Advanced Search Results For "Grossman, Matt"

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 "Grossman, Matt"
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BRAFV600E induces reversible mitotic arrest in human melanocytes via microRNA-mediated suppression of AURKB

Publication Type:Academic Journal

Source(s):eLife, Vol 10 (2021)

Abstract:Benign melanocytic nevi frequently emerge when an acquired BRAFV600E mutation triggers unchecked proliferation and subsequent arrest in melanocytes. Recent observations have challenged the role of oncogene-induced senescence in melanocytic nevus format...

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Prediction and Classification of Alzheimer’s Disease Based on Combined Features From Apolipoprotein-E Genotype, Cerebrospinal Fluid, MR, and FDG-PET Imaging Biomarkers

Publication Type:Academic Journal

Source(s):Frontiers in Computational Neuroscience, Vol 13 (2019)

Abstract:Alzheimer's disease (AD), including its mild cognitive impairment (MCI) phase that may or may not progress into the AD, is the most ordinary form of dementia. It is extremely important to correctly identify patients during the MCI stage because this is...

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The Influence of Cerebrospinal Fluid Abnormalities and APOE 4 on PHF-Tau Protein: Evidence From Voxel Analysis and Graph Theory

Publication Type:Academic Journal

Source(s):Frontiers in Aging Neuroscience, Vol 11 (2019)

Abstract:Mild cognitive impairment (MCI) is a transitional state between the cognitive changes in normal aging and Alzheimer’s disease (AD), which induces abnormalities in specific brain regions. Previous studies showed that paired helical filaments Tau (PHF-Ta...

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New Perspective for Non-invasive Brain Stimulation Site Selection in Mild Cognitive Impairment: Based on Meta- and Functional Connectivity Analyses

Publication Type:Academic Journal

Source(s):Frontiers in Aging Neuroscience, Vol 11 (2019)

Abstract:BackgroundNon-invasive brain stimulation (NIBS) has been widely used to treat mild cognitive impairment (MCI). However, there exists no consensus on the best stimulation sites.ObjectiveTo explore potential stimulation locations for NIBS treatment in pa...

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Developments in Agricultural Soil Quality and Health: Reflections by the Research Committee on Soil Organic Matter Management

Publication Type:Academic Journal

Source(s):Frontiers in Environmental Science, Vol 7 (2019)

Abstract:The North Central Education and Research Activity Committee (NCERA-59) was formed in 1952 to address how soil organic matter formation and management practices affect soil structure and productivity. It is in this capacity that we comment on the scienc...

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Performing Sparse Regularization and Dimension Reduction Simultaneously in Multimodal Data Fusion

Publication Type:Academic Journal

Source(s):Frontiers in Neuroscience, Vol 13 (2019)

Abstract:Collecting multiple modalities of neuroimaging data on the same subject is increasingly becoming the norm in clinical practice and research. Fusing multiple modalities to find related patterns is a challenge in neuroimaging analysis. Canonical correlat...

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Quantitative 18F-AV1451 Brain Tau PET Imaging in Cognitively Normal Older Adults, Mild Cognitive Impairment, and Alzheimer's Disease Patients

Publication Type:Academic Journal

Source(s):Frontiers in Neurology, Vol 10 (2019)

Abstract:Recent developments of tau Positron Emission Tomography (PET) allows assessment of regional neurofibrillary tangles (NFTs) deposition in human brain. Among the tau PET molecular probes, 18F-AV1451 is characterized by high selectivity for pathologic tau...

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Conversion Discriminative Analysis on Mild Cognitive Impairment Using Multiple Cortical Features from MR Images

Publication Type:Academic Journal

Source(s):Frontiers in Aging Neuroscience, Vol 9 (2017)

Abstract:Neuroimaging measurements derived from magnetic resonance imaging provide important information required for detecting changes related to the progression of mild cognitive impairment (MCI). Cortical features and changes play a crucial role in revealing...

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