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How does aquaculture activity affect phytoplankton functional groups in Gaoyou Lake, China
Publication Type: Academic Journal
Source(s): Journal of Freshwater Ecology, Vol 38, Iss 1 (2023)
Abstract: AbstractAquaculture in lakes is an important human activity that could accelerate eutrophication. Its impacts on aquatic ecosystems have attracted extensive attention. This study was carried out in Gaoyou Lake, China. We investigated environmental vari...
Evolving cognition of the JAK-STAT signaling pathway: autoimmune disorders and cancer
Publication Type: Academic Journal
Source(s): Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-24 (2023)
Abstract: Abstract The Janus kinase (JAK) signal transducer and activator of transcription (JAK-STAT) pathway is an evolutionarily conserved mechanism of transmembrane signal transduction that enables cells to communicate with the exterior environment. Various c...
Influence of fishery management on trophic interactions and biomass fluxes in Lake Taihu based on a trophic mass-balance model exercise on a long-term data series
Publication Type: Academic Journal
Source(s): Ecological Indicators, Vol 158, Iss , Pp 111343- (2024)
Abstract: With increasing anthropogenic activities, freshwater ecosystems around the world are becoming increasingly affected by various pressures, including eutrophication, overfishing, and irrational stocking, which may have a negative impact on the food web s...
Effects of 3‐HAA on HCC by Regulating the Heterogeneous Macrophages—A scRNA‐Seq Analysis
Publication Type: Academic Journal
Source(s): Advanced Science, Vol 10, Iss 16, Pp n/a-n/a (2023)
Abstract: Abstract Kynurenine derivative 3‐hydroxyanthranilic acid (3‐HAA) is known to regulate the immune system and exhibit anti‐inflammatory activity by inhibiting T‐cell cytokine secretion and influencing macrophage activity. However, the definite role of 3‐...
New insights into iNKT cells and their roles in liver diseases
Publication Type: Academic Journal
Source(s): Frontiers in Immunology, Vol 13 (2022)
Abstract: Natural killer T cells (NKTs) are an important part of the immune system. Since their discovery in the 1990s, researchers have gained deeper insights into the physiology and functions of these cells in many liver diseases. NKT cells are divided into tw...
The role of transketolase in human cancer progression and therapy
Publication Type: Academic Journal
Source(s): Biomedicine & Pharmacotherapy, Vol 154, Iss , Pp 113607- (2022)
Abstract: Transketolase (TKT) is an enzyme that is ubiquitously expressed in all living organisms and has been identified as an important regulator of cancer. Recent studies have shown that the TKT family includes the TKT gene and two TKT-like (TKTL) genes; TKTL...
Long noncoding RNA SNHG4: a novel target in human diseases
Publication Type: Academic Journal
Source(s): Cancer Cell International, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract: Abstract Recently, long noncoding RNAs (lncRNAs) have attracted great attention from researchers. LncRNAs are non-protein-coding RNAs of more than 200 nucleotides in length. Multiple studies have been published on the relationship between lncRNA expres...
Transcriptome profiling reveals toxicity mechanisms following sertraline exposure in the brain of juvenile zebrafish (Danio rerio)
Publication Type: Academic Journal
Source(s): Ecotoxicology and Environmental Safety, Vol 242, Iss , Pp 113936- (2022)
Abstract: Sertraline (SER) is one of the most commonly detected antidepressants in the aquatic environment that can negatively affect aquatic organisms at low concentrations. Despite some knowledge on its acute toxicity to fish, the effects of chronic SER exposu...
Multi-Omics Characterizes the Effects and Mechanisms of CD1d in Nonalcoholic Fatty Liver Disease Development
Publication Type: Academic Journal
Source(s): Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Abstract: Nonalcoholic fatty liver disease (NAFLD) is a class of metabolic-associated liver diseases. Aberrant lipid consumption plays an important role in NAFLD pathogenesis. It has been shown CD1d can bind to multiple different lysophospholipids and associated...
Prostaglandin E2 and Receptors: Insight Into Tumorigenesis, Tumor Progression, and Treatment of Hepatocellular Carcinoma
Publication Type: Academic Journal
Source(s): Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Abstract: Hepatocellular carcinoma (HCC) is a common primary liver cancer with ∼750,000 annual incidence rates globally. PGE2, usually known as a pro-inflammatory cytokine, is over-expressed in various human malignancies including HCC. PGE2 binds to EP receptors...