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Advanced Search Results For "Guarrera, Simonetta"

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 "Guarrera, Simonetta"
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Blood cell DNA methylation biomarkers in preclinical malignant pleural mesothelioma: The EPIC prospective cohort.

Publication Type: Academic Journal

Source(s): International Journal of Cancer; Feb2023, Vol. 152 Issue 4, p725-737, 13p

Abstract: Copyright of International Journal of Cancer is the property of John Wiley & Sons, Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may...

Integrative genomic and transcriptomic analyses illuminate the ontology of HER2-low breast carcinomas.

Publication Type: Academic Journal

Source(s): Genome Medicine; 8/29/2022, Vol. 14 Issue 1, p1-16, 16p

Abstract: Copyright of Genome Medicine is the property of BioMed Central and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or emai...

MicroRNA 146a is associated with diabetic complications in type 1 diabetic patients from the EURODIAB PCS.

Publication Type: Academic Journal

Source(s): Journal of Translational Medicine; 11/25/2021, Vol. 19 Issue 1, p1-10, 10p

Abstract: Copyright of Journal of Translational Medicine is the property of BioMed Central and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print,...

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

Publication Type: Periodical

Source(s): Nature Genetics; September 2021, Vol. 53 Issue: 9 p1311-1321, 11p

Abstract: Characterizing genetic influences on DNA methylation (DNAm) provides an opportunity to understand mechanisms underpinning gene regulation and disease. In the present study, we describe results of DNAm quantitative trait locus (mQTL) analyses on 32,851 ...

Role of TGF-β1 haplotypes in the occurrence of myocardial infarction in young Italian patients

Publication Type: Academic Journal

Source(s): BMC Medical Genetics, Vol 9, Iss 1, p 13 (2008)

Abstract: Abstract Background Transforming growth factor beta 1 (TGF-β1) gene play an important role in the acute myocardial infarction (AMI), however no investigation has been conducted so far in young AMI patients. In this study, we evaluated the influence of ...

Integrative genomic and transcriptomic analyses illuminate the ontology of HER2-low breast carcinomas

Publication Type: Academic Journal

Source(s): Genome Medicine, Vol 14, Iss 1, Pp 1-16 (2022)

Abstract: Abstract Background The “HER2-low” nomenclature identifies breast carcinomas (BCs) displaying a HER2 score of 1+/2+ in immunohistochemistry and lacking ERBB2 amplification. Whether HER2-low BCs (HLBCs) constitute a distinct entity is debated. Methods W...

MicroRNA 146a is associated with diabetic complications in type 1 diabetic patients from the EURODIAB PCS

Publication Type: Academic Journal

Source(s): Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-10 (2021)

Abstract: Abstract Background MicroRNA-146a-5p (miR-146a-5p) is a key regulator of inflammatory processes. Expression of miR-146a-5p is altered in target organs of diabetic complications and deficiency of miR-146a-5p has been implicated in their pathogenesis. We...

Associations of autozygosity with a broad range of human phenotypes

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)

Abstract: Inbreeding depression has been observed in many different species, but in humans a systematic analysis has been difficult so far. Here, analysing more than 1.3 million individuals, the authors show that a genomic inbreeding coefficient (FROH) is associ...

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