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Advanced Search Results For "Guido Papa"

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 "Guido Papa"
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Sequences in the cytoplasmic tail of SARS-CoV-2 Spike facilitate expression at the cell surface and syncytia formation

Publication Type: Academic Journal

Source(s): Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)

Abstract: The Spike protein of SARS-CoV-2 has a C-terminal cytoplasmic tail. Here the authors show that this tail binds trafficking machinery via sequences that appear optimised to ensure that Spike accumulates at the site of viral budding in the Golgi but that ...

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Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7

Publication Type: Academic Journal

Source(s): Cell Reports, Vol 35, Iss 13, Pp 109292- (2021)

Abstract: Summary: We report severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ΔH69/V70 in multiple independent lineages, often occurring after acquisition of receptor binding motif replacements such as N439K and Y453F, known to increase binding...

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Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion.

Publication Type: Academic Journal

Source(s): PLoS Pathogens, Vol 17, Iss 1, p e1009246 (2021)

Abstract: Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) infects cells by binding to the host cell receptor ACE2 and undergoing virus-host membrane fusion. Fusion is triggered by the protease TMPRSS2, which processes the viral Spike (S) protein to ...

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Viroplasms: Assembly and Functions of Rotavirus Replication Factories

Publication Type: Academic Journal

Source(s): Viruses, Vol 13, Iss 1349, p 1349 (2021)

Abstract: Viroplasms are cytoplasmic, membraneless structures assembled in rotavirus (RV)-infected cells, which are intricately involved in viral replication. Two virus-encoded, non-structural proteins, NSP2 and NSP5, are the main drivers of viroplasm formation....

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An Inhibitory Motif on the 5'UTR of Several Rotavirus Genome Segments Affects Protein Expression and Reverse Genetics Strategies.

Publication Type: Academic Journal

Source(s): PLoS ONE, Vol 11, Iss 11, p e0166719 (2016)

Abstract: Rotavirus genome consists of eleven segments of dsRNA, each encoding one single protein. Viral mRNAs contain an open reading frame (ORF) flanked by relatively short untranslated regions (UTRs), whose role in the viral cycle remains elusive. Here we inv...

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Discussing the applicability of a process core ontology and aspects of its internal quality.

Publication Type: Academic Journal

Source(s): Software Quality Journal; Dec2022, Vol. 30 Issue 4, p1003-1038, 36p

Abstract: Copyright of Software Quality Journal is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, downloa...

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Rotavirus Spike Protein VP4 Mediates Viroplasm Assembly by Association to Actin Filaments.

Publication Type: Academic Journal

Source(s): Journal of Virology. Sep2022, Vol. 96 Issue 17, p1-23. 23p.

Abstract: Rotavirus (RV) viroplasms are cytosolic inclusions where both virus genome replication and primary steps of virus progeny assembly take place. A stabilized microtubule cytoskeleton and lipid droplets are required for the viroplasm formation, which invo...

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Cor Triatriatum Dexter: Contrast Echocardiography Is Key to the Diagnosis of a Rare but Treatable Cause of Neonatal Persistent Cyanosis.

Publication Type: Academic Journal

Source(s): Children; May2022, Vol. 9 Issue 5, p676-N.PAG, 6p

Abstract: Copyright of Children is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for in...

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The Effectiveness of Chlorhexidine and Air Polishing System in the Treatment of Candida albicans Infected Dental Implants: An Experimental In Vitro Study

Publication Type: Academic Journal

Source(s): Antibiotics, Vol 9, Iss 179, p 179 (2020)

Abstract: Background: Peri-implantitis is an inflammatory disease with an increasing diffusion rate which can affect the long-term survival of a prosthetic rehabilitation. The present study focused on the decontaminating efficacy of chlorhexidine and air polishi...

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Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity.

Publication Type: Academic Journal

Source(s): Nature; Mar2022, Vol. 603 Issue 7902, p706-714, 9p

Abstract: Copyright of Nature is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articl...

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