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Epidemiology of eating disorders: population, prevalence, disease burden and quality of life informing public policy in Australia—a rapid review
Publication Type: Academic Journal
Source(s): Journal of Eating Disorders, Vol 11, Iss 1, Pp 1-46 (2023)
Abstract: Plain English summary Our understanding of the prevalence and impact of eating disorders has improved significantly over the past 20-years. Research highlights that rates of eating disorders are increasing. To inform the development of the Eating Disor...
Personalized recurrence risk assessment following the birth of a child with a pathogenic de novo mutation
Publication Type: Academic Journal
Source(s): Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract: PREGCARE is a new strategy for families who had a child with a pathogenic de novo mutation, that efficiently identifies couples at higher recurrence risk due to parental mosaicism, while reassuring many others that their recurrence risk is negligible.
Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018
Publication Type: Academic Journal
Source(s): BMC Medicine, Vol 20, Iss 1, Pp 1-24 (2022)
Abstract: Abstract Background Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is still among the leading causes of disease burden and mortality in sub-Saharan Africa (SSA), and the world is not on track to meet targets set for end...
Global investments in pandemic preparedness and COVID-19: development assistance and domestic spending on health between 1990 and 2026
Publication Type: Academic Journal
Source(s): The Lancet Global Health, Vol 11, Iss 3, Pp e385-e413 (2023)
Abstract: Summary: Background: The COVID-19 pandemic highlighted gaps in health surveillance systems, disease prevention, and treatment globally. Among the many factors that might have led to these gaps is the issue of the financing of national health systems, e...
Measuring exercise in eating disorder patients: a Delphi study to aggregate clinical and research knowledge
Publication Type: Academic Journal
Source(s): Journal of Eating Disorders, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract: Plain English summary Exercise is an important feature of most eating disorders. Researchers have found that people with an eating disorder exercise because they feel driven to do so, or because it helps them cope with negative emotions. This type of e...
Quantifying the impact of immune history and variant on SARS-CoV-2 viral kinetics and infection rebound: A retrospective cohort study
Publication Type: Academic Journal
Source(s): eLife, Vol 11 (2022)
Abstract: Background: The combined impact of immunity and SARS-CoV-2 variants on viral kinetics during infections has been unclear. Methods: We characterized 1,280 infections from the National Basketball Association occupational health cohort identified between ...
Screening and evaluation of biomass upgrading strategies for sustainable transportation fuel production with biomass-derived volatile fatty acids
Publication Type: Academic Journal
Source(s): iScience, Vol 25, Iss 11, Pp 105384- (2022)
Abstract: Summary: Biomass conversion to fuels and chemicals is crucial to decarbonization, but choosing an advantageous upgrading pathway out of many options is challenging. Rigorously evaluating all candidate pathways (process simulation, product property test...
Pharmacokinetics of hydroxychloroquine in paediatric lupus: data from a novel, direct-to-family clinical trial
Publication Type: Academic Journal
Source(s): Lupus Science and Medicine, Vol 9, Iss 1 (2022)
Abstract: Objective Determine the pharmacokinetics (PK) and exposure–response of hydroxychloroquine (HCQ) and desethylhydroxychloroquine (DHCQ) in paediatric SLE (pSLE).Methods We conducted an exploratory phase 2, direct-to-family trial. Children enrolled in the...
Molecular mechanism of Afadin substrate recruitment to the receptor phosphatase PTPRK via its pseudophosphatase domain
Publication Type: Academic Journal
Source(s): eLife, Vol 11 (2022)
Abstract: Protein tyrosine phosphatase receptor-type kappa (PTPRK) is a transmembrane receptor that links extracellular homophilic interactions to intracellular catalytic activity. Previously we showed that PTPRK promotes cell–cell adhesion by selectively dephos...
Mapping development and health effects of cooking with solid fuels in low-income and middle-income countries, 2000–18: a geospatial modelling study
Publication Type: Academic Journal
Source(s): The Lancet Global Health, Vol 10, Iss 10, Pp e1395-e1411 (2022)
Abstract: Summary: Background: More than 3 billion people do not have access to clean energy and primarily use solid fuels to cook. Use of solid fuels generates household air pollution, which was associated with more than 2 million deaths in 2019. Although local...