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Advanced Search Results For "Holden, Emily"

1 - 10 of 406 results for
 "Holden, Emily"
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Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)

Abstract: Abstract Whole genome sequencing of SARS-CoV-2 has occurred at an unprecedented scale, and can be exploited for characterising outbreak risks at the fine-scale needed to inform control strategies. One setting at continued risk of COVID-19 outbreaks are...

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INTERSTAARS: Attention training for infants with elevated likelihood of developing ADHD: A proof-of-concept randomised controlled trial

Publication Type: Academic Journal

Source(s): Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)

Abstract: Abstract Attention-deficit/hyperactivity disorder (ADHD) is first diagnosed during middle childhood, when patterns of difficulty are often established. Pre-emptive approaches that strengthen developing cognitive systems could offer an alternative to po...

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A SARS-CoV-2 antigen rapid diagnostic test for resource limited settings

Publication Type: Academic Journal

Source(s): Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Abstract: Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative agent of COVID-19 disease. RT-qPCR has been the primary method of diagnosis; however, the required infrastructure is lacking in many developing countries and the vir...

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Disturbance has lasting effects on functional traits and diversity of grassland plant communities

Publication Type: Academic Journal

Source(s): PeerJ, Vol 10, p e13179 (2022)

Abstract: Background Localized disturbances within grasslands alter biological properties and may shift species composition. For example, rare species in established communities may become dominant in successional communities if they exhibit traits well-suited t...

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Examining adherence to oral anticancer medications through a human factors engineering framework: Protocol for a scoping review.

Publication Type: Academic Journal

Source(s): PLoS ONE, Vol 17, Iss 9, p e0274963 (2022)

Abstract: BackgroundThe number of oral anticancer medications has increased over the past few decades, opening new possibilities in cancer care and improving convenience for patients and caregivers. However, adherence levels continue to be suboptimal, potentiall...

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The impact of viral mutations on recognition by SARS-CoV-2 specific T cells

Publication Type: Academic Journal

Source(s): iScience, Vol 24, Iss 11, Pp 103353- (2021)

Abstract: Summary: We identify amino acid variants within dominant SARS-CoV-2 T cell epitopes by interrogating global sequence data. Several variants within nucleocapsid and ORF3a epitopes have arisen independently in multiple lineages and result in loss of reco...

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Implementing stakeholder engagement to explore alternative models of consent: An example from the PREP-IT trials

Publication Type: Academic Journal

Source(s): Contemporary Clinical Trials Communications, Vol 22, Iss , Pp 100787- (2021)

Abstract: Introduction: Cluster randomized crossover trials are often faced with a dilemma when selecting an optimal model of consent, as the traditional model of obtaining informed consent from participant's before initiating any trial related activities may no...

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Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7

Publication Type: Academic Journal

Source(s): Cell Reports, Vol 35, Iss 13, Pp 109292- (2021)

Abstract: Summary: We report severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ΔH69/V70 in multiple independent lineages, often occurring after acquisition of receptor binding motif replacements such as N439K and Y453F, known to increase binding...

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Managing work flow in high enrolling trials: The development and implementation of a sampling strategy in the PREPARE trial

Publication Type: Academic Journal

Source(s): Contemporary Clinical Trials Communications, Vol 21, Iss , Pp 100730- (2021)

Abstract: Introduction: Pragmatic trials in comparative effectiveness research assess the effects of different treatment, therapeutic, or healthcare options in clinical practice. They are characterized by broad eligibility criteria and large sample sizes, which ...

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