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Advanced Search Results For "Holter IM"

1 - 10 of 19 results for
 "Holter IM"
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Nursing services administration in Norway.

Publication Type: Academic Journal

Source(s): International Nursing Review; May/Jun91, Vol. 38 Issue 3, p83-85, 3p

Abstract: Copyright of International Nursing Review is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, dow...

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A Preclinical Trial and Molecularly Annotated Patient Cohort Identify Predictive Biomarkers in Homologous Recombination-deficient Pancreatic Cancer.

Publication Type: Academic Journal

Source(s): Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2020 Oct 15; Vol. 26 (20), pp. 5462-5476. Date of Electronic Publication: 2020 Aug 14.

Abstract: Purpose: Pancreatic ductal adenocarcinoma (PDAC) arising in patients with a germline BRCA1 or BRCA2 (g BRCA ) mutation may be sensitive to platinum and PARP inhibitors (PARPi). However, treatment stratification based on g BRCA mutational status alone i...

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Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.

Publication Type: Academic Journal

Source(s): Behavioural brain research [Behav Brain Res] 2018 Oct 15; Vol. 352, pp. 187-196. Date of Electronic Publication: 2017 Sep 29.

Abstract: Since decades, model organisms have provided an important approach for understanding the mechanistic basis of human diseases. The German Mouse Clinic (GMC) was the first phenotyping facility that established a collaboration-based platform for phenotype...

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Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial.

Publication Type: Academic Journal

Source(s): Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2018 Mar 15; Vol. 24 (6), pp. 1344-1354. Date of Electronic Publication: 2017 Dec 29.

Abstract: Purpose: To perform real-time whole genome sequencing (WGS) and RNA sequencing (RNASeq) of advanced pancreatic ductal adenocarcinoma (PDAC) to identify predictive mutational and transcriptional features for better treatment selection. Experimental Desi...

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Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms.

Publication Type: Academic Journal

Source(s): Molecular neurobiology [Mol Neurobiol] 2017 Dec; Vol. 54 (10), pp. 8242-8262. Date of Electronic Publication: 2016 Dec 02.

Abstract: Stress experience modulates behavior, metabolism, and energy expenditure of organisms. One molecular hallmark of an acute stress response is a rapid induction of immediate early genes (IEGs) such as c-Fos and Egr family members. IEG transcription in ne...

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Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice.

Publication Type: Academic Journal

Source(s): Nature communications [Nat Commun] 2017 Jul 24; Vol. 8 (1), pp. 155. Date of Electronic Publication: 2017 Jul 24.

Abstract: Dietary restriction regimes extend lifespan in various animal models. Here we show that longevity in male C57BL/6J mice subjected to every-other-day feeding is associated with a delayed onset of neoplastic disease that naturally limits lifespan in thes...

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Lack of evidence for germline RNF43 mutations in patients with serrated polyposis syndrome from a large multinational study.

Publication Type: Report

Source(s): Gut [Gut] 2017 Jun; Vol. 66 (6), pp. 1170-1172. Date of Electronic Publication: 2016 Aug 31.

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DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma.

Publication Type: Academic Journal

Source(s): Nature medicine [Nat Med] 2017 Mar; Vol. 23 (3), pp. 386-395. Date of Electronic Publication: 2017 Jan 30.

Abstract: Developmental tumors in children and young adults carry few genetic alterations, yet they have diverse clinical presentation. Focusing on Ewing sarcoma, we sought to establish the prevalence and characteristics of epigenetic heterogeneity in geneticall...

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Functional maturation of developing interneurons in the molecular layer of mouse dentate gyrus.

Publication Type: Academic Journal

Source(s): Brain research [Brain Res] 2007 Dec; Vol. 1186, pp. 56-64. Date of Electronic Publication: 2007 Oct 12.

Abstract: The dentate gyrus is the main target for cortical inputs to the hippocampal formation and is particularly strongly controlled by synaptic inhibition. Many GABAergic interneurons migrate from the dentate molecular layer towards their final position in t...

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Generation and characterization of dickkopf3 mutant mice.

Publication Type: Academic Journal

Source(s): Molecular and cellular biology [Mol Cell Biol] 2006 Mar; Vol. 26 (6), pp. 2317-26.

Abstract: dickkopf (dkk) genes encode a small family of secreted Wnt antagonists, except for dkk3, which is divergent and whose function is poorly understood. Here, we describe the generation and characterization of dkk3 mutant mice. dkk3-deficient mice are viab...

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